How hexafluoroisopropanol solvent promotes Diels-Alder cycloadditions: metadynamics simulations.

The solvent effects in Diels-Alder cycloadditions were studied by using molecular dynamics simulations with explicit molecular treatments for both substrates and solvents. Energy decomposition analysis was used to investigate the role of H-bonding networks of hexafluoroisopropanol solvent in promoting both reactivity and regioselectivity.

Transcriptome Analysis Identifies Novel Genes Associated with Low-Temperature Seed Germination in Sweet Corn.

Typically, sweet corn, particularly sweet corn, has low seed vigor owing to its high sugar and low starch content, which is a major problem in sweet corn production, particularly at low temperatures. There is considerable variation in the germination rates among sweet corn varieties under low-temperature conditions, and the underlying mechanisms behind this phenomenon remain unclear. In this study, we screened two inbred sweet corn lines (tolerant line L282 and sensitive line L693) differing in their low-temperature germination rates; while no difference was observed in their germination rates at normal temperatures.

Ab Initio Metadynamics Simulations of Hexafluoroisopropanol Solvent Effects: Synergistic Role of Solvent H-Bonding Networks and Solvent-Solute C-H/π Interactions.

The solvent effects in Friedel-Crafts cycloalkylation of epoxides and Cope rearrangement of aldimines were investigated by using ab initio molecular dynamics simulations. Explicit molecular treatments were applied for both reactants and solvents. The reaction mechanisms were elucidated via free energy calculations based on metadynamics simulations.

Experiment on monitoring leakage of landfill leachate by parallel potentiometric monitoring method.

The accumulation of municipal solid waste (MSW) in landfills often becomes a serious pollution source of geological environment and groundwater. The geological environment is the carrier of the landfill, and also the main pollution object of the landfill. The main pollution modes of the landfill site to the surrounding geological environment are purging, flushing, leachate, etc.

Multi-factor settlement prediction around foundation pit based on SSA-gradient descent model.

With the rise of machine learning, a lot of excellent algorithms are used for settlement prediction. Backpropagation (BP) and Elman are two typical algorithms based on gradient descent, but their performance is greatly affected by the random selection of initial weights and thresholds, so this paper chooses Sparrow Search Algorithm (SSA) to build joint model. Then, two sets of land subsidence monitoring data generated during the excavation of a foundation pit in South China are used for analysis and verification.

Association of Met/Val polymorphism of BDNF gene with Alzheimer's disease in Chinese patients.

Alzheimer's is the most common cause of dementia in the elderly. In this disease, genetic and environmental factors are involved. In Alzheimer's, changes of nucleotide 196 (G> A) or valine polymorphism of 66-methionine in the BDNF gene is a risk factor for brain-derived neurogenic factors.

Transcriptome Analysis of Near-Isogenic Lines Provides Novel Insights into Genes Associated with Seed Low-Temperature Germination Ability in Maize ( L.).

Maize originated from tropical regions and is extremely sensitive to low temperature during germination. Our previous work identified a major QTL, , for low temperature germination ability (LTGA) of maize. Here, we introgressed from the tolerant line L220 into the sensitive line PH4CV to generate two near isogenic lines NIL and NIL.

Sensitive Detection of Serum Creatinine Based on β-Cyclodextrin-Ferrocenylmethanol Modified Screen-printed Electrode.

Ferrocenylmethanol (Fc-OH) is included in β-cyclodextrin (β-CD) to form the β-CD-Fc-OH complex by host-guest supramolecular interaction. β-CD dissociates from the β-CD-Fc-OH complex due to the conversion of Fc-OH to Fc-OH under a stimulus of oxidant. In our study, Fc-OH is oxidized after a series of enzymatic reactions of creatinine, which blocks the other means for oxidation of Fc-OH.

[QTL analysis for percentage of exserted stigma in rice (Oryza sativa L.)].

Percentage of exserted stigmas (PES) was investigated in Hainan by using a population of 127 DH population derived from a cross between a high-PES indica variety Zaiyeqing 8 (ZYQ 8) and a low-PES japonica variety Jingxi 17(JX 17) and its molecular linkage map of 234 markers. Two QTLs (qPES-2, qPES-3) for PES were located on chromosome 2 and 3, respectively. There is no difference between the QTLs for single stigma exsertation and total PES, but the only QTL for dual stigma exsertation located on chromosome 2, whose positive additive effect was from ZYQ 8.