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Publications by authors named "Xinmei Shu"

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Estrogen Enhances Expression in Theca Cells of Chicken Hierarchical Ovarian Follicles by Increasing LSD1Ser54p Level Through GSK3β Phosphorylation at 216th Tyrosine.
Yanhong Zhang Conghao Zhong Xinmei Shu Qingxin Liu Yunliang Jiang

Biomolecules

October 2024

Article Synopsis
  • The study investigates how estrogen influences the development of chicken ovarian follicles by regulating the phosphorylation of specific proteins, particularly lysine demethylase 1A (LSD1) and glycogen synthase kinase 3 beta (GSK3β).
  • It was found that estrogen increases the phosphorylation of GSK3β, enhancing its interaction with LSD1, which in turn boosts levels of LSD1Ser54p.
  • The research indicates that this process promotes the upregulation of a gene involved in cholesterol biosynthesis, potentially increasing estrogen production in chicken ovarian cells.
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