Publications by authors named "Xinmao Ma"
Background And Purpose: It is unknown the neural mechanisms of developmental stuttering (DS). The aim of this study was to investigate the changes in the structural morphology of the brain in Chinese children who stutter.
Methods: A case-control study was conducted to collect magnetic resonance imaging data from stuttering and non-stuttering children, thereby analyzing whole-brain gray matter volume and cortical morphological changes in stuttering children.
Article Synopsis
- Children with spinal muscular atrophy (SMA) are at significant risk for low bone mineral density (BMD) and bone fragility, particularly those aged 6.3 years and older.
- A study analyzed data from 66 SMA patients and found that 28.8% had low BMD, with age being the most influential factor on BMD levels.
- Regular monitoring of BMD is recommended for all SMA children, especially as they age, to prevent complications related to bone health.
Article Synopsis
- Menkes disease is a rare genetic disorder that affects copper metabolism, leading to various health issues, particularly in the nervous system and connective tissues.
- Diagnostic markers like serum copper and ceruloplasmin levels are unreliable, making imaging techniques crucial for identifying the disease.
- A case study of a 4-month-old boy highlighted significant neurological symptoms and imaging findings, confirming Menkes disease through genetic testing, but unfortunately, treatment did not improve his condition, resulting in his death three months later.
Background: Stuttering affects approximately 5% of children; however, its neurological basis remains unclear. Identifying imaging biomarkers could aid in early detection. Accordingly, we investigated resting-state cerebral blood flow (CBF) in children with developmental stuttering.
View Article and Find Full Text PDFTourette syndrome (TS) is a developmental neuropsychiatric disorder characterized by repetitive, stereotyped, involuntary tics, the neurological basis of which remains unclear. Although traditional resting-state MRI (rfMRI) studies have identified abnormal static functional connectivity (FC) in patients with TS, dynamic FC (dFC) remains relatively unexplored. The rfMRI data of 54 children with TS and 46 typically developing children (TDC) were analyzed using group independent component analysis to obtain independent components (ICs), and a sliding-window approach to generate dFC matrices.
View Article and Find Full Text PDFObjective: Myocardial edema is an early manifestation of chemotherapy-related myocardial injury. In this study, we used cardiac magnetic resonance (CMR) T2 mapping to assess myocardial edema and its changes during chemotherapy for gynecologic malignancies.
Methods: We enrolled 73 patients receiving chemotherapy for gynecologic malignancies, whose the latest cycle was within one month before the beginning of this study, and 41 healthy volunteers.
Objectives: Cancer chemotherapy potentially increases the risk of myocardial ischemia. This study assessed myocardial microvascular function by cardiac magnetic resonance (CMR) first-pass perfusion in patients treated with chemotherapy for gynecologic malignancies.
Methods: A total of 81 patients treated with chemotherapy for gynecologic malignancies and 39 healthy volunteers were prospectively enrolled and underwent CMR imaging.
Background: Anaplastic lymphoma kinase (ALK)-positive histiocytosis is a rare type of histiocytosis that could affect multiple systems in children and adults. 10 cases of ALK-positive histiocytosis invading the central nervous system (CNS) have been reported. Herein, we report a case of ALK-positive histiocytosis invading the central nervous system and lungs and the details of follow-up of tumor dynamic changes during treatment.
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