Publications by authors named "Xinlei Yuan"
Human milk oligosaccharides could prevent pathogenic bacterial infections in neonates; however, direct in vivo anti-infection evidence was still lacking. Here, we systematically evaluated the effects of 2'-fucosyllactose (2'-FL) and 3'-sialyllactose (3'-SL) on the structural development and functional maturation in neonates and their defense against enteroaggregative infection. It was found that supplementation with 2'-FL and 3'-SL improved the resistance of weaned mice to enteroaggregative .
View Article and Find Full Text PDFObesity, a global disease, can lead to different chronic diseases and a series of social health problems. Lifestyle changes, especially dietary changes, are the most effective way to treat obesity. , a novel food, has attracted much attention.
View Article and Find Full Text PDFArticle Synopsis
- Recent research indicates that OPL is the dominant triacylglycerol in human breast milk in China, with potential benefits for infant nutrition through enhanced absorption of fatty acids and calcium.
- * In neonatal mice, OPL supplementation led to increased body weight, longer intestines, and improved intestinal health by promoting the development of intestinal structures and boosting specific stem cell markers.
- * OPL also positively influenced the gut microbiota, shifting it towards maturity, increasing beneficial bacterial populations, and enhancing fecal butyrate levels, which are linked to improved gut health.