Untargeted metabolomics in with habitat heterogeneity and the key abiotic factors affecting its active ingredients.

Introduction: is a rare, endangered herb with diverse pharmacological properties. Understanding the main metabolite types and characteristics of wild is important for efficiently utilizing resources and examining quality according to origin.

Methods: Samples were collected from the main production areas across five regions in Fujian Province, China.

Utilization of functional agro-waste residues for oyster mushroom production: Nutritions and active ingredients in healthcare.

A large amount of agro-industrial residues are produced from the planting, production and processing of traditional Chinese herbs. As a tonic, edible, and economical herb, root has been extensively developed into medicine and functional food. However, thousands of tons of aerial parts (stems, leaves, flowers and fruits) have been directly discarded after harvest each year.

Nutritional Characterization and Untargeted Metabolomics of Oyster Mushroom Produced Using var. Stems and Leaves as Substrates.

var. (AMM) is an edible and medicinal material and is commonly used in East Asia. According to the pharmacopeia of China, the dried root of AMM is medicinal.

Untargeted Metabolomics Reveals Multiple Phytometabolites in the Agricultural Waste Materials and Medicinal Materials of .

has been used in traditional Chinese medicine for hundreds of years, where it has been used to treat anaemia, fatigue, a weak spleen, and stomach problems, among other ailments. The roots of are considered medicinal, while the aerial parts are always directly discarded after harvest in autumn or winter. Some studies have shown that the stems and leaves of also contain a variety of active metabolites, including saponins, flavonoids, terpenoids, and polysaccharides.

Mechanism of Shengmai Injection on Anti-Sepsis and Protective Activities of Intestinal Mucosal Barrier in Mice.

Objective: To study the mechanism of Shengmai Injection (SMI, ) on anti-sepsis and protective activities of intestinal mucosal barrier.

Methods: The contents of 11 active components of SMI including ginsenoside Rb1, Rb2, Rb3, Rd, Re, Rf, Rg1, Rg2, ophioposide D, schisandrol A and schisantherin A were determined using ultra-performance liquid chromatography. Fifty mice were randomly divided into the blank, the model, the low-, medium- and high-dose SMI groups (0.

Akkermansia muciniphila: A potential novel mechanism of nuciferine to improve hyperlipidemia.

Background: Intestinal microbiota is a novel drug target of metabolic diseases, especially for those with poor oral bioavailability. Nuciferine, with poor bioavailability, has an anti-hyperlipidemic effect at low dosages.

Purpose: In the present study, we aimed to explore the role of intestinal microbiota in the anti-hyperlipidemic function of nuciferine and identify the key bacterial targets that might confer the therapeutic actions.

Investigation of the Mechanism of Shengmai Injection on Sepsis by Network Pharmacology Approaches.

Shengmai injection (SMI) contains Ginsen Radix et Rhizoma Rubra, , and Schisandrae Chinensis Fructus. It is used as a supportive herbal medicine in the management of sepsis, systemic inflammatory response syndrome, and septic or hemorrhagic shock. An UPLC method was established to identify and evaluate SMI fingerprints.