DTBP-mediated cross-dehydrogenative coupling of 3-aryl benzofuran-2(3)-ones with toluenes/phenols for all-carbon quaternary centers.

We have developed a transition-metal free protocol for efficient cross-dehydrogenative coupling of 3-aryl benzofuran-2(3)-ones and toluenes/phenols using DTBP as an oxidant. A diverse range of 3-aryl benzofuran-2(3)-ones, toluenes, and phenols undergo C-H bond cleavage to generate all-carbon quaternary centers in good yields, making this protocol useful for the synthesis of complex molecules. A gram scale experiment was performed in good yield.

Cu(I)-Catalyzed C-H Alkenylation of Tertiary C(sp)-H Bonds of 3-Aryl Benzofuran-2()-ones to Give - and -Styrene Containing Quaternary Carbon Centers with 99/1 Regioselectivity.

The synthesis of isomerically pure olefins containing all-carbon quaternary centers is a challenging issue. Herein, we developed an efficient protocol for the synthesis of ()-olefins (27 examples, yield up to 97%, / up to 99/1) and ()-olefins (16 examples, yield up to 94%, / up to 99/1) containing all-carbon quaternary centers. This protocol is adopted for the copper-catalyzed regioselective C-H alkenylation of the tertiary C(sp)-H bond of 3-aryl benzofuran-2()-ones with alkyne and alkenes.

A fluorescent sensor for fast detection of peroxynitrite by removing of C=N in a benzothiazole derivative.

A simple structured reaction-based probe for peroxynitrite (ONOO) was developed by using benzothiazole hydrazone base of the excited-state intramolecular proton transfer (ESIPT) dye. It was constructed from 2-hydrazinylpyridine and 3-(benzo[d]thiazol-2-yl)-2-hydroxy-5-methylbenzaldehyde which possesses itself weak fluorescence and displayed prominent fluorescence response towards ONOO by oxidizes the C=N bond to an aldehyde in aqueous solution. The probe exhibited excellent selectivity and high sensivity towards ONOO with a low dectection limit of 5.