Publications by authors named "Xinju Li"

Objective: To explore the mechanism of acupuncture to relieve diabetic proteinuria in Diabetic Kidney Disease (DKD).

Methods: A total of 10 male Sprague-Dawley rats were randomly selected as the negative control group (NC), and a further 30 rats were fed a high-fat diet (HFD) and intraperitoneal streptozotocin (STZ). The DKD model rats in the model group (DKD) and the acupuncture group (DKD + Acu) were randomly assigned.

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The accumulation of soil organic carbon (SOC) is crucial for the development and ecosystem function restoration of reclaimed mine soils (RMSs). To optimize reclamation management practices, this study aims to explore the factors and underlying mechanisms influencing the recovery of SOC and its components in RMSs from a systemic perspective using complex network theory (CNT). This study focused on coal mining subsidence areas in the eastern mining regions of China, comparing reclaimed cultivated land with surrounding non-subsided cultivated land.

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The rapid and accurate acquisition of soil property information, especially the soil salinity (SS), is required for saline soil management in the Yellow River Delta (YRD). In this study, Lijin County and Kenli District were selected as study area. Unmanned aerial vehicle (UAV) multispectral data and soil sample data were acquired from March 25 to 28, 2019.

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Rapid and large-scale estimation of soil salt content (SSC) and organic matter (SOM) using multi-source remote sensing is of great significance for the real-time monitoring of arable land quality. In this study, we simultaneously predicted SSC and SOM on arable land in the Yellow River Delta (YRD), based on ground measurement data, unmanned aerial vehicle (UAV) hyperspectral imagery, and Landsat-8 multispectral imagery. The reflectance averaging method was used to resample UAV hyperspectra to simulate the Landsat-8 OLI data (referred to as fitted multispectra).

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Objective: Xiaoyao San (XYS) is a medicinal preparation that is commonly employed in China for the treatment of anxiety disorders (AD). Despite suggestions that it may offer certain advantages in this context, there are no reliable evidence-based studies regarding its efficacy at present. The present study was developed to gauge the efficacy and safety of XYS for the treatment of AD in a systematic manner.

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Soil organic carbon (SOC) of reclaimed minesoil (RMS) is regarded as an important part of terrestrial SOC, and SOC losses of RMSs occur during the substantial soil compaction and the removal, storage and backfilling of the topsoil, which lead to poor soil structure. The filling of alternative soil substrates is considered to disturb the soil structure of RMSs, however, how SOC pool changes in the RMSs filled with various substrates and the mechanisms are less clearly understood. Therefore, a study on reclaimed area filled with three typical alternative soil substrates, including mining waste reclamation (MWR), river sand reclamation (RSR) and river mud reclamation (RMR), was started in mining area of Eastern China, where total SOC, labile SOC fractions, stable SOC fraction and soil physicochemical properties were measured.

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Drug resistance has become the major obstacle for the treatment of non-small cell lung cancer (NSCLC). Circular RNAs (circRNAs) are tightly linked to the development of drug resistance of NSCLC. Herein, we tested the function of circ_0002360 in the Taxol resistance of NSCLC.

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Objective: To evaluate the clinical efficacy of traditional Chinese medicine in the treatment of arrhythmia.

Methods: The researchers searched CNKI, VIP, WF, PubMed, Web of Science, and Cochrane Library with the set-up themes as randomized controlled trials (RCTs) on the clinical efficacy of traditional Chinese medicine in the treatment of arrhythmia. This research evaluated all the retrieve literature and conducted selection based on the evaluation.

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Activation is an effective method to improve adsorption capacity of coal gangue, however, most activated gangues reported have limited adsorption capacity for phosphate because of the electronegativity, affecting their use in agricultural production and environmental protection. In order to enhance the phosphate absorption capacity of coal gangue through alkali-activation, three alkali-activated silicate coal gangue according to fine-size (AS-FCG), medium-size (AS-MCG), and large-size (AS-LCG) were prepared through grinding, calcining (800 °C) and stimulating with Ca(OH) solution (0.1 M), and raw coal gangue (RCG) was used as control.

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Objective: Chaihu Jia Longgu Muli decoction (CLMD) is widely used in the treatment of poststroke depression (PSD) in China. Some evidences show that it has advantages, but there lacks reliable evidence. This study aims to systematically evaluate the efficacy and safety of CLMD in the treatment of PSD.

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Neurofibromatosis type 1 (NF1), an autosomal dominant and multisystem disorder, is generally considered to be caused by NF1 inactivation. However, there are also numerous studies showing that Neurofibromatosis type 1-like phenotype can be caused by the abnormalities in the other genes. Through targeted parallel sequencing, whole-exome sequencing, de novo genomic sequencing, and RNA isoform sequencing, we identified a germline V2097M variation in CSPG4 gene probably increased susceptibility to a NF1-like phenotype family.

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Background: To analyze and evaluate EGFR, KRAS, and PIK3CA gene mutation rates and clinical distribution in patients with different types of lung cancer METHOD: A total of 221 lung cancer patients treated in our hospital between January 2016 and June 2019 were enrolled. Tissue and whole blood samples were collected and analyzed to determine the mutation status of EGFR, KRAS, and PIK3CA genes. The gene exon mutation rates were determined.

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The Dawen River Watershed (DRW), an important sub-basin of the Yellow River, has been experiencing substantial climatic and anthropogenic stresses. Identifying how stressors relate to shifts in vegetation growth is critical for maintaining the health and stability of its regional ecosystems. To address this, we constructed a 20-year dataset (1999-2018) reflecting changes in satellite-based normalized difference vegetation index (NDVI), climate variables, and land use in the DRW.

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In recent years, soil salinization in the Yellow River Delta under the effects of hydrology, climate and human activities have become increasingly prominent. Based on the 20 Landsat series images of Hekou, Kenli, Dongying districts and Lijin County of Dongying City selected from 1985 to 2018, numerical regression correction method was used to perform image spectral consistency conversion. The partial least squares regression method was used to construct quantitative inversion models of soil salt content.

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Background: Insomnia is a common sleep disorder, which seriously affects people's quality of life and work ability. In China, auricular therapy and moxibustion therapy have a long history in treating insomnia. Clinical studies have shown that auricular point and moxibustion can effectively improve insomnia symptoms.

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Background: As a traditional Chinese medicine external treatment method, acupuncture is characterized by simple operation, significant treatment effect and few side effects. Dry eye, also known as conjunctival xerosis, refers to pathological changes in tissues of ocular surface caused by abnormal tear quality and quantity or dynamics due to various reasons, which can cause red and swollen eyes, congestion, and severe cases may result in lesions of the conjunctiva. Clinical practice shows that acupuncture has a certain therapeutic effect on dry eye, but there is a lack of medical evidence.

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Background: Obsessive-compulsive disorder is common, chronic mental disorder, which is characterized by recurrent, unwanted, or intrusive thoughts and repetitive behaviors or mental action. Acupuncture and moxibustion, as a popular form of complementary and alternative therapy, have the advantages of low side effects, high safety, and low cost. The research showed that acupuncture and moxibustion have a good clinical efficacy on obsessive-compulsive disorder.

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Objective: To observe the therapeutic effect of needling technique (acupuncture for regulating spleen and stomach) on diabetic gastroparesis (DGP), and to explore its possible mechanism.

Methods: A total of 128 patients with DGP were randomized into an observation group (64 cases, 4 cases dropped off) and a control group (64 cases, 4 cases dropped off). On the basis of intervention on controlling blood glucose by western medication, needling technique was adopted at Zhongwan (CV 12), Zusanli (ST 36), Yinlingquan (SP 9), Xuehai (SP 10), Sanyinjiao (SP 6), Diji (SP 8), etc.

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Land subsidence monitoring provides information required when developing land use plans and allows for proactive management of subsidence issues. However, it has been challenging to accurately detect land subsidence areas, especially those under waterbodies. This study evaluated the applicability of integrated use of the optical Landsat-8 OLI and microwave Sentinel-1A TOPSAR imagery to delineate subsidence areas and quantify subsidence rates in a typical coal mining area of North China Plain.

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Background: Fire needle therapy is an ancient external treatment method of traditional Chinese medicine. This therapy is simple to operate and has fewer side effects. Gouty arthritis (GA) is common disease that is often characterized by high excruciating pain on joint.

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This systematic review and meta-analysis aimed at evaluating the effect of traditional Chinese medicine (TCM) Bufei granule on stable chronic obstructive pulmonary disease (COPD). We retrieved data from PubMed, Web of Science, EMBASE, the Cochrane Central Register of Controlled Trials, CNKI, Wanfang, and WeiPu (VIP) for studies focusing on whether the TCM Bufei granule would be effective in treating stable COPD. No language restriction and blinding were used.

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Background: Minimally invasive esophagectomy (MIE) has become a good option in the surgical treatment of esophageal cancer. Cervical esophagogastric anastomoses (CEGA) are widely used during esophagectomy. However, CEGA are related with a higher incidence of anastomotic complications.

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Swertiamarin (STM) is a natural compound from Franch. (Gentianaceae) that exhibits various pharmacological effects. The current study tested the potential neuroprotective activity of STM in human neuroblastoma SH-SY5Y cells challenged with oxygen-glucose deprivation/reoxygenation (OGDR).

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Objective: To observe the clinical therapeutic effect of "Tiaoshen Zhitong" (mental regulating and pain relieving) needling and its influence on serological indicators in the treatment of post-stroke shoulder pain, so as to provide new therapeutic thoughts and approach for post-stroke shoulder pain.

Methods: A total of 80 inpatients with post-stroke shoulder pain were randomly divided into a control group (routine needling, 39 cases) and an observation group ("Tiaoshen Zhitong" needling, 41 cases) according to the random number table. Patients of the two groups accepted basic medication treatment including anticoagulants, hypotensive drugs, hypoglycermic drugs, lipid-lowering drugs, etc.

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Coal mining has environmental impacts on surrounding areas, including heavy metal contamination of soil. This study explores the feasibility of using hyperspectral remote sensing to determine the heavy metal (Cr, Ni, Cu, Zn, Cd, Pb) content of soils in a coal-mining area in the city of Zoucheng, Shandong Province, China. We used a plasma mass spectrometer to measure the heavy metal contents of soils and an ASD Field Spec4 spectrometer to measure soil hyperspectral data.

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