The compositions, characteristics, health benefits and applications of anthocyanins in crops.

crops, well known for their nutritional and medicinal value, encompass a diverse range of species and varieties, many of which are rich in anthocyanins. These flavonoid pigments not only contribute to the vibrant colors of plants but also possess significant antioxidant, anti-inflammatory, and neuroprotective properties. This review provides an in-depth analysis of the distribution, composition, and health benefits of anthocyanins in crops, highlighting their potential applications in the food industry and medicine.

Covalent Anchoring of Mechanical Polymer for Highly Stable Zinc Metal Batteries.

Artificial interfacial protective coatings (IPCs) on Zn anodes provide a viable solution for suppressing dendritic growth by spatially confining and homogenizing the Zn flux. However, repeated Zn deformation during electroplating/stripping cycles can lead to the rupture or exfoliation of IPCs, as well as the formation of detrimental interfacial gaps. Herein, a highly durable IPC is developed on a Zn substrate using a mechanically robust fluorinated polyimide nanofilm (FPI).

Inorganic arsenic in aquatic products in Shenzhen, China from 2018 to 2024: Levels, temporal variation and health risk assessment.

Aquatic products are a significant source of arsenic exposure, with inorganic arsenic (iAs) posing a significant risk to humans. This study assessed iAs levels in 1191 aquatic products from Shenzhen, China (2018-2024), and estimated health risks. Shellfish had lower mean iAs levels (0.

Autophagy in High-Fat Diet and Streptozotocin-Induced Metabolic Cardiomyopathy: Mechanisms and Therapeutic Implications.

Metabolic cardiomyopathy, encompassing diabetic and obese cardiomyopathy, is an escalating global health concern, driven by the rising prevalence of metabolic disorders such as insulin resistance, type 1 and type 2 diabetes, and obesity. These conditions induce structural and functional alterations in the heart, including left ventricular dysfunction, fibrosis, and ultimately heart failure, particularly in the presence of coronary artery disease or hypertension. Autophagy, a critical cellular process for maintaining cardiac homeostasis, is frequently disrupted in metabolic cardiomyopathy.

Eu-Doped TiO Coatings One-Step Preparation Enhance Macrophage Polarization and Osseointegration of Implants.

The controllable regulation of immune and osteogenic processes plays a critical role in the modification of biocompatible materials for tissue regeneration. In this study, titanium dioxide-europium coatings (MAO/Eu) were prepared on the surface of a titanium alloy (Ti-6Al-4V) a one-step process combining microarc oxidation (MAO) and doping. The incorporation of Eu significantly improved the hydrophilic and mechanical properties of the TiO coatings without altering their morphology.

Binary Doping of Strontium-Magnesium to Bioactive Glasses to Enhance Antibacterial and Osteogenic Effects.

Bone defects that exceed the critical defect value, resulting from fractures and diseases, are often difficult to heal. Although bone tissue engineering is a promising treatment for extensive osseous defects, orthopedic-implant-related infections increase the likelihood of failure. Bioactive glass (BG) has been widely used in the manufacture of artificial bone scaffolds, owing to its excellent biocompatibility and osteoinductivity.

Impact of SARS-CoV-2 inactivated vaccine on symptoms following omicron variant breakthrough infection.

The SARS-CoV-2 Omicron variant and its sublineages continue to circulate widely. Clinical outcomes with this variant differ among individuals, primarily influenced by host immunity. Previous studies have explored the relationship between immune responses and severe diseases in infected or convalescent patients.

Global stability boundary analysis and verification of aviation pressure servo-controlled actuator system.

In this paper, the mathematical model of the aviation pressure servo valve controlled actuator system(APSVCAS) considering nonlinearity is established based on a jet pipe pressure servo valve in this article. And the dynamic characteristics and stability boundary of APSVCAS are analyzed, which provides theoretical guidance for the actual composition and the determination of parameters. Firstly, a jet-tube two-stage pressure servo valve for aviation hydraulic system is designed, and an accurate model of APSVCAS is established considering multiple nonlinear factors.

Advances in Molecular Dynamics-Based Characterization of Water and Ion Adsorption and Transport in C-S-H Gels.

Cementitious material durability is affected by the transport and adsorption of water molecules and ions in the nanopore channels of cement hydration products. Hydrated calcium silicate (C-S-H) accounts for about 70% of the hydration product. It determines the mechanical properties of cementitious materials and their internal transport properties.

Increased health risk from co-exposure to polycyclic aromatic hydrocarbons, phthalates, and per- and polyfluoroalkyl substances: Epidemiological insight from e-waste workers in Hong Kong.

The alarming surge in electronic waste (e-waste) in Hong Kong has heightened concerns regarding occupational exposure to a myriad of pollutants. Among these, polycyclic aromatic hydrocarbons (PAHs), phthalates (PAEs), and per- and polyfluoroalkyl substances (PFASs) are prevalent and known for their harmful effects, including the induction of oxidative stress and DNA damage, thereby contributing to various diseases. This study addresses gaps in knowledge by investigating exposure levels of these pollutants-measured via hydroxylated PAHs (OH-PAHs), phthalate metabolites (mPAEs), and PFASs-in urine from 101 e-waste workers and 100 office workers.

Localized Water Restriction in Ternary Eutectic Electrolytes for Ultra-Low Temperature Hydrogen Batteries.

Proton batteries are promising candidates for next-generation large-scale energy storage in extreme conditions due to the small ionic radius and efficient transport of protons. Hydrogen gas, with its low working potentials, fast kinetics, and stability, further enhances the performance of proton batteries but necessitates the development of novel electrolytes with low freezing points and reduced corrosion. This work introduces a localized water restriction strategy by incorporating a tertiary component with a high donor number, which forms strong bonds with water molecules.

Neonicotinoid residues in fruits and vegetables in Shenzhen: Assessing human exposure and health risks.

The extensive use of neonicotinoids (NEOs) in agricultural production has led to their pervasive presence in various environmental matrices, including human samples. Given the central role of fruits and vegetables in daily human diets, it is crucial to evaluate the levels of NEOs residues and their potential health risks. In this study, 3104 vegetable samples and 1567 fruit samples from the Shenzhen city were analyzed.

Co-exposure to parabens, bisphenol A, and triclosan and the associations with dyslipidemia in Chinese older adults: The mediation effect of oxidative stress.

Dyslipidemia is a prevalent metabolic disorder in older adults and has negative effects on cardiovascular health. However, the combined effect of paraben, bisphenol A (BPA), and triclosan (TCS) exposure on dyslipidemia and the underlying mechanisms remain unclear. This cross-sectional study recruited 486 individuals ≥60 years in Shenzhen, China.

Multi-channel electron transfer induced by polyvanadate in metal-organic framework for boosted peroxymonosulfate activation.

Catalytic peroxymonosulfate (PMS) activation processes don't solely rely on electron transfer from dominant metal centers due to the complicated composition and interface environment of catalysts. Herein the synthesis of a cobalt based metal-organic framework containing polyvanadate [VO] cluster, Co(VO)(bpy) (bpy = 4,4'-bipyridine), is presented. The catalyst demonstrates superior degradation activity toward various micropollutants, with higher highest occupied molecular orbital (HOMO), via nonradical attack.

Drug-induced liver injury in children: A nationwide cohort study from China.

Background & Aims: Currently, there is limited knowledge on the clinical profile of drug-induced liver injury (DILI) in Chinese children. We aimed to assess the clinical characteristics, suspected drugs, and outcomes associated with pediatric DILI in China.

Methods: This nationwide, multicenter, retrospective study, conducted between 2012 and 2014, analyzed 25,927 cases of suspected DILI at 308 medical centers using the inpatient medical register system.

Per- and polyfluoroalkyl substances in Chinese commercially available red swamp crayfish (Procambarus clarkii): Implications for human exposure and health risk assessment.

The extensive utilization of per- and polyfluoroalkyl substances (PFASs) has led to their pervasive presence in the environment, resulting in contamination of aquatic products. Prolonged exposure to PFASs has been linked to direct hepatic and renal damage, along with the induction of oxidative stress, contributing to a spectrum of chronic ailments. Despite the recent surge in popularity of red swamp crayfish as a culinary delicacy in China, studies addressing PFASs' exposure and associated health risks from their consumption remain scarce.

Low-threshold cavity-enhanced superfluorescence in polyhedral quantum dot superparticles.

Due to the unique and excellent optical performance and promising prospect for various photonics applications, cavity-enhanced superfluorescence (CESF) in perovskite quantum dot assembled superstructures has garnered wide attention. However, the stringent requirements and high threshold for achieving CESF limit its further development and application. The high threshold of CESF in quantum dot superstructures is mainly attributed to the low radiation recombination rate of the quantum dot and the unsatisfactory light field limiting the ability of the assembled superstructures originating from low controllability of self-assembly.

Microcephaly Gene Deficiency Induces p19ARF-Dependent Cell Cycle Arrest and Senescence.

has been identified as the causal gene for primary microcephaly type 1, a neurodevelopmental disorder characterized by reduced brain size and delayed growth. As a multifunction protein, MCPH1 has been reported to repress the expression of TERT and interact with transcriptional regulator E2F1. However, it remains unclear whether MCPH1 regulates brain development through its transcriptional regulation function.

Activating innate immune responses repolarizes hPSC-derived CAR macrophages to improve anti-tumor activity.

Generation of chimeric antigen receptor macrophages (CAR-Ms) from human pluripotent stem cells (hPSCs) offers new prospects for cancer immunotherapy but is currently challenged by low differentiation efficiency and limited function. Here, we develop a highly efficient monolayer-based system that can produce around 6,000 macrophages from a single hPSC within 3 weeks. Based on CAR structure screening, we generate hPSC-CAR-Ms with stable CAR expression and potent tumoricidal activity in vitro.

Concentrations, sources and health risk of bisphenols in red swamp crayfish (Procambarus clarkii) from South-Eastern China.

Bisphenol analogs (BPs) are extensively employed in commercial and industrial products and they have been found in a variety of environmental matrices and human samples. The red swamp crayfish (Procambarus clarkii) has been a trendy food in China in recent decades. However, the levels of BPs in Chinese crayfish and the associated hazards of human exposure remain unknown.

Improved phase-to-height mapping method combine with device attitude.

Phase-to-height mapping is one of the important processes in three dimensional phase measurement profilometry. But, in traditional phase-to-height mapping method, the measurement accuracy is affected by device attitude, so it needs saving a large amount of mapping equations to achieve high-quality phase-to-height mapping. In order to improve that, this paper proposes an improved phase-to-height mapping method combine with device attitude.