Publications by authors named "Xini Wu"
Article Synopsis
- Mammalian cardiac troponin I (cTnI) has an amino-terminal extension with serine targets that get phosphorylated to improve heart relaxation during increased heart activity.
- Researchers found that some species like shrews and moles evolved to mimic this phosphorylation process, allowing them to maintain extremely high resting heart rates.
- The study suggests that humans could improve heart function in heart failure by considering the removal of a weakly spliced exon found in cTnI, which has implications for heart health.
