Uranium Extraction from Seawater via Hydrogen Bond Porous Organic Cages.

Uranium (U), a high-performing, low-emission energy source, is driving sustainable economic growth. Herein, we synthesized two crystalline phases (HPOC-α and β) by an unreported amidoxime organic cage used for uranium capture. The revealed crystal structures and uranium adsorption test showed that accessible functional groups were essential to uranyl ions sorption.

Synthesis of Tetracyclic-Fused Dihydroindeno[2,1-]chromenes via Palladium-Catalyzed Alkyne Insertion and C-H Bond Activation.

An unprecedented Pd-catalyzed cascade alkyne insertion/Heck/C-H activation reaction of -iodophenyl alkenyl ethers and diarylacetylenes has been developed. Diversified tetracyclic-fused dihydroindeno[2,1-]chromenes bearing a quaternary center were constructed in an efficient, straightforward, and atom-economic way with good to excellent yields. The protocol features high bonding efficiency, operational simplicity, broad substrate scope, and easy scale-up.

LsKN1 and LsOFP6 synergistically regulate the bolting time by modulating the gibberellin pathway in lettuce.

Bolting time is an important agronomic trait in lettuce (Lactuca sativa) production. Premature bolting significantly reduces crop quality and marketability. Here, we report map-based cloning and characterization of a LsKN1 gene that controls bolting in lettuce.

Starch digestion and physiochemical properties of a newly developed rice variety with low glycemic index.

This study aimed to clarify the starch digestion characteristics and related physicochemical properties of the newly developed low-GI rice variety, Ditangliangyou 335 (D335), in comparison with two widely grown rice varieties, Xiangzaoxian 45 (X45) and Zhongzao 39 (Z39). The results showed that D335 had an active digestion duration (286 min) that was 101-190 % shorter, a glucose production rate (1.06 mg g min) that was 57-73 % slower, and a total glucose production (303 mg g) that was 11-19 % less than X45 and Z39.

Research on multi-optical axis online compensation alignment method for space environment simulation system.

Aiming at the problem that the error of multi-optical axis alignment is difficult to control in the simulation calibration test, a multi-optical axis dynamic compensation alignment method for the space environment simulation system is proposed. The effect of optical axis disturbance on the signal detection link was analyzed to obtain the alignment accuracy requirements, the optical axis alignment error compensation mechanism was established, the target simulation system with long pupil distance was designed, the alignment error transfer model based on topology structure was constructed, and the test prototype was built. The test results show that the static attitude alignment resolution is better than 3" and the position alignment resolution is better than 11µm.

Research on the background stray light suppression method of a dim target projector based on the orthogonal polarization extinction principle.

Aiming at the problem of background stray light affecting the display of dim target scenes in existing projectors, a stray light suppression optical engine based on a polarizer is proposed. First, the effect of the background stray light of traditional LCOS target projectors on the display of dim targets is analyzed with simulation, and the sources of stray light in the target projector were analyzed as well. Secondly, we theoretically analyze the causes of different stray light paths and stray light polarization states, propose the method of stray light suppression based on the polarizer, and calculate the rotation angle of the polarizer.

Fabrication of 3D CuFeO/Cu hierarchical nanostructures on carbon fiber paper by simple hydrothermal method for efficient detection of malachite green, sunset yellow and tartrazine in food samples.

In this study, a hydrothermal process was utilized to grow mixed-valence CuFeO/Cu nanosheets on carbon fiber paper, forming a three-dimensional hierarchical electrode (CuFeO/Cu@CFP). The ordered array structure, coupled with the porous bowl-like structure, enhances the exposure of more electrode active sites and facilitates analyte penetration, thus enhancing the electrode sensing performance. As a binder-free sensor, the CuFeO/Cu@CFP sensor exhibited remarkable sensitivity in detecting Malachite Green (MG), Sunset Yellow (SY) and Tartrazine (TA) over wide concentration ranges: 0.

The OsMYC2-JA feedback loop regulates diurnal flower-opening time via cell wall loosening in rice.

Diurnal flower-opening time (DFOT), the time of spikelet opening during the day, is an important trait for hybrid rice (Oryza sativa L.) seed production. Hybrids between indica and japonica rice varieties have strong heterosis, but the parental lines usually have different, nonoverlapping DFOTs.

Association of physical performance with cognitive impairment in middle-aged to older haemodialysis patients: a multicentre cross-sectional observational study.

Objective: To determine the prevalence of cognitive impairment (CI) among middle-aged to older patients receiving maintenance haemodialysis (MHD) and to investigate the potential association between CI and physical performance.

Methods: This cross-sectional observational study enrolled participants aged 55-85 years who received MHD. Cognitive status was assessed using the Mini Mental State Examination (MMSE).

Spent Lithium-Ion Batteries Derived CoO for Electrocatalytic Polyethylene Terephthalate Plastic Recycling.

Spent lithium-ion batteries (LIBs) are an essential secondary resource containing valuable metal elements. Transforming spent LIBs into efficient catalysts through a simple process presents a promising strategy to address both metal resource scarcity and clean energy challenges. Herein, a deep eutectic solvent-assisted synthesis of CoO material from spent LIBs is proposed.

EZH2-H3K27me3-mediated silencing of mir-139-5p inhibits cellular senescence in hepatocellular carcinoma by activating TOP2A.

Background: Epigenetic alterations play an important role in hepatocellular carcinoma (HCC) development. Enhancer of zeste homolog 2 (EZH2) is a well-known epigenetic modifier that functions as an oncogene in tumors by promoting the H3K27me3-mediated transcriptional repression of tumor suppressor genes. "Senescent cells" has been proposed as a possible core component of the hallmarks of cancer conceptualization.

Photoinduced Nonvolatile Resistive Switching Behavior in Oxygen-Doped MoS for a Neuromorphic Vision System.

Controlling resistance by external fields provides fascinating opportunities for the development of novel devices and circuits, such as temperature-field-induced superconductors, magnetic-field-triggered giant magnetoresistance devices, and electric-field-operated flash memories. In this work, we demonstrate a light-triggered nonvolatile resistive switching behavior in oxygen-doped MoS. The two-terminal devices exhibit stable light-modulated resistive switching characteristics and optically tunable synaptic properties with an on/off ratio of up to 10.

Enhanced sensitivity and durability in photodetector of Ag/nanocellulose/Si via plasma-assisted synthesis.

Position-sensitive detectors (PSDs) based on the lateral photovoltaic effect (LPE) are widely used for precision displacement and angle measurement. However, high temperatures can lead to the thermal decomposition or oxidation of nanomaterials frequently utilized in PSDs, and can ultimately affect the performance. In this study, we present a PSD based on Ag/nanocellulose/Si that maintains a maximum sensitivity of 416.

Development and validation of a ligand-receptor pairs signature to predict outcome and provide a therapeutic strategy in gastric cancer.

Background: An important factor in tumor development and progression is the tumor microenvironment (TME), which is heterogeneous. Previous studies have mainly investigated the expression profile and prognostic values of genes in gastric cancer (GC) at the cell population level but neglected the interactions and heterogeneity between cells.

Methods: The pattern of ligand-receptor (LR) interactions was delineated on a scRNA-seq dataset containing 44,953 cells from nine GC patients and a fourth bulk RNA-seq dataset including data from 1159 GC patients.

Prognostic role and immune infiltration characteristics of EI24 in multiple cancer types.

Background: The autophagy-associated transmembrane protein EI24 is associated with cancer growth and patient survival. We aimed to explore the prognostic role and immune infiltration characteristics of EI24 at a pan-cancer level.

Methods: We collected data from multiple databases to explore the expression and prognostic role of EI24 in various cancers.

Relationship between serum CHIP levels with cardiovascular disease in maintenance haemodialysis patients.

Many preclinical studies reported that the carboxyl terminus of Hsp70-interacting protein (CHIP) has cardiovascular protective effects. This study was designed to explore whether CHIP is related with cardiovascular disease (CVD) in maintanence haemodialysis (MHD) patients. 217 MHD patients and 150 healthy controls were recruited, serum CHIP concentration and clinical characteristics were measured.

Targeting the E3 ligase NEDD4 as a novel therapeutic strategy for IGF1 signal pathway-driven gastric cancer.

The IGF1 signal pathway is highly activated in some subtype of gastric cancer(GC) that exhibits poor survival and chemotherapy resistance. Although the results of clinical trials of anti-IGF1R monoclonal antibodies and IGF-1R inhibitors have been mostly disappointing in unselected cancer patients, some patients benefit from anti-IGF1R therapy in these failed studies. Therefore, it is necessary to characterize the complex IGF signaling in GC and help refine the strategies targeting the IGF1 pathway.

PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development.

The Ets transcription factor PU.1 is essential for inducing the differentiation of monocytes, macrophages, and B cells in fetal liver and adult bone marrow. PU.

Seismic Response Evaluation of High-Steep Slopes Supported by Anti-Slide Piles with Different Initial Damage Based on Shaking Table Test.

In order to study the instability development process of the slope reinforced by anti-slide piles under earthquake conditions, the dynamic response characteristics of the slope are usually taken as the main characteristics, and the model test and numerical simulation are the main research methods. In this paper, a shaking table model test is designed and completed to investigate the influence of anti-slide piles with different initial damage on the failure mode of high and steep slope under earthquake conditions. The changes in velocity, strain and natural frequency during slope vibration are tested in combination with cloud maps when sinusoidal waves of different accelerations with a peak value of 5 Hz are applied.

Pyroptosis impacts the prognosis and treatment response in gastric cancer via immune system modulation.

Pyroptosis plays a vital role in the development of cancers; however, its role in regulating immune cell infiltration in tumor microenvironment (TME) and pyroptosis-related molecular subtypes remain unclear. Herein, we comprehensively analyzed the molecular subtypes mediated by the pyroptosis-related genes (PRGs) in gastric cancer (GC). Three pyroptosis patterns were determined with distinct TME cell-infiltrating characteristics and prognosis.

Comparative Analysis of Efficacy and Prognosis of Hemodialysis and Peritoneal Dialysis for End-Stage Renal Disease: A Meta-analysis.

Objective: This meta-analysis is aimed at systematically assessing the efficacy and prognosis of hemodialysis (HD) and peritoneal dialysis (PD) in the treatment of end-stage renal disease (ESRD).

Methods: China National Knowledge Infrastructure, VIP, SinoMed, Cochrane Library, PubMed, and Embase databases were searched for relevant studies to evaluate the two different dialysis methods for ESRD. The search time was set from 2010 to 2021.

Engineering of rice varieties with enhanced resistances to both blast and bacterial blight diseases via CRISPR/Cas9.

Rice blast and bacterial blight represent two of major diseases having devastating impact on the yield of rice in most rice-growing countries. Developments of resistant cultivars are the most economic and effective strategy to control these diseases. Here, we used CRISPR/Cas9-mediated gene editing to rapidly install mutations in three known broad-spectrum blast-resistant genes, Bsr-d1, Pi21 and ERF922, in an indica thermosensitive genic male sterile (TGMS) rice line Longke638S (LK638S).

Correlation of Serum Adropin Levels with Risk Factors of Cardiovascular Disease in Hemodialysis Patients.

Many preclinical studies have shown that adropin has physiological effects such as regulating glucose, lipid, and energy metabolism, protecting endothelial cells and antiatherosclerosis. Our aim is to explore whether adropin is correlated with risk factors of cardiovascular disease (CVD) in hemodialysis (HD) patients. We recruited 170 HD patients and 120 healthy controls.