The Association Between Eye Disease and Incidence of Dementia: Systematic Review and Meta-Analysis.

Objectives: To better demonstrate the relationship between common eye diseases and the risk of dementia, we conducted a systematic review and meta-analysis of cohort studies to investigate the relationship between common eye diseases and dementia.

Design: Systematic review and meta-analysis.

Setting And Participants: Patients with common eye diseases.

Biotransformation of 12-hydroxystearic acid to gamma-decalactone: Comparison of two separation systems.

Biotransformation of natural products to the natural flavoring, gamma-decalactone (GDL), has attracted considerable attention. However, improving its yield is challenging due to its high feedback inhibition of yeast cells, which lowers the productivity of the biotransformation process. In this study, we compared two in situ separation processes established by adding either resin (HZ-816) or cyclopentasiloxane (DC345) to a biotransformation medium and investigated their efficiency and effect on yeast metabolism.