Integrative analysis of multiple cell death model for precise prognosis and drug response prediction in gastric cancer.

Background: Gastric cancer (GC) is a common upper gastrointestinal tumor. However, the evaluation of prognosis and treatment response in patients with gastric cancer remains a challenge. Programmed cell death (PCD) is one of the important terminal paths for the cells of metazoans, and is involved in a variety of biological events that include morphogenesis, maintenance of tissue homeostasis, and elimination of harmful cells.

Nonreciprocal field transformation with active acoustic metasurfaces.

Field transformation, as an extension of the transformation optics, provides a unique means for nonreciprocal wave manipulation, while the experimental realization remains a substantial challenge as it requires stringent material parameters of the metamaterials, e.g., purely nonreciprocal bianisotropic parameters.

Acoustic Amplifying Diode Using Nonreciprocal Willis Coupling.

We propose a concept called acoustic amplifying diode combining signal isolation and amplification in a single device. The signal is exponentially amplified in one incident direction with no reflection and is perfectly absorbed in another. The reflection is eliminated from the device in both directions with impedance matching, preventing backscattering to the signal source.

Digitally virtualized atoms for acoustic metamaterials.

By designing tailor-made resonance modes with structured atoms, metamaterials allow us to obtain constitutive parameters outside their limited range from natural materials. Nonetheless, tuning the constitutive parameters depends on our ability to modify the physical structure or external circuits attached to the metamaterials, posing a fundamental challenge to the range of tunability in many real-time applications. Here, we propose the concept of virtualized metamaterials on their signal response function to escape the boundary inherent in the physical structure of metamaterials.