IEEE Trans Neural Netw Learn Syst
September 2024
Deep reinforcement learning (DRL) has been widely adopted in various applications, yet it faces practical limitations due to high storage and computational demands. Dynamic sparse training (DST) has recently emerged as a prominent approach to reduce these demands during training and inference phases, but existing DST methods achieve high sparsity levels by sacrificing policy performance as they rely on the absolute magnitude of connections for pruning and randomly generating connections. Addressing this, our study presents a generic method that can be seamlessly integrated into existing DST methods in DRL to enhance their policy performance while preserving their sparsity levels.
View Article and Find Full Text PDFElectrocatalytic nitrate reduction to ammonia holds great promise for developing green technologies for electrochemical ammonia energy conversion and storage. Considering that real nitrate resources often exhibit low concentrations, it is challenging to achieve high activity in low-concentration nitrate solutions due to the competing reaction of the hydrogen evolution reaction, let alone considering the catalyst lifetime. Herein, we present a high nitrate reduction performance electrocatalyst based on a Co nanosheet structure with a gradient dispersion of Ru, which yields a high NH Faraday efficiency of over 93% at an industrially relevant NH current density of 1.
View Article and Find Full Text PDFBackground: Developing novel germplasm by using wheat wild related species is an effective way to rebuild the wheat resource bank. The Psathyrostachys huashanica Keng (P. huashanica, 2n = 2x = 14, NsNs) is regarded as a superior species to improve wheat breeding because of its multi-resistance, early maturation and numerous tiller traits.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
April 2024
Lifelong deep reinforcement learning (DRL) approaches are commonly employed to adapt continuously to new tasks without forgetting previously acquired knowledge. While current lifelong DRL methods have shown promising advancements in retaining acquired knowledge, they suffer from significant adaptation efforts (i.e.
View Article and Find Full Text PDFInteractions between microorganisms and plants can stimulate plant growth and promote nitrogen cycling. Nitrogen fertilizers are routinely used in agriculture to improve crop growth and yield; however, poor use efficiency impairs the optimal utilization of such fertilizers. Differences in the microbial diversity and plant growth of rice soil under different nitrogen application conditions and the expression of nitrogen-use efficiency-related genes have not been previously investigated.
View Article and Find Full Text PDFWheat sheath blight caused by the necrotic fungal pathogen is responsible for severe damage to bread wheat. Reactive oxygen species (ROS) are vital for stress resistance by plants and their homeostasis plays an important role in wheat resistance to sheath blight. Valine-glutamine (VQ) proteins play important roles in plant growth and development, and responses to biotic and abiotic stresses.
View Article and Find Full Text PDFRice is the main food crops with the higher capacity for cadmium (Cd) uptake, necessitating the urgent need for remediation measures to address Cd in paddy soil. Reasonable agronomic methods are convenient and favorable for fixing the issue. In this study, a pot experiment was employed to evaluate the effects of two foliar (NaHPO, SDP; KHPO, PDP) and two solid phosphate fertilizers (double-superphosphate, DSP; calcium-magnesium phosphate, CMP) on uptake and remobilization of Cd in rice plants under the low-P and rich-Cd soil.
View Article and Find Full Text PDFObjective: To evaluate the association between traditional laboratory findings and death, and to find risk factors for death in infants with early onset sepsis (EOS).
Study Design: This was a single-center, case-control, retrospective trial conducted between January 2020 and August 2021. Infants with EOS were enrolled and divided into two groups based on outcome before hospital discharge: non-survivors (Mortality group) and survivors (Survival group).
Crossing the blood-brain barrier in primates is a major obstacle for gene delivery to the brain. Adeno-associated viruses (AAVs) promise robust, non-invasive gene delivery from the bloodstream to the brain. However, unlike in rodents, few neurotropic AAVs efficiently cross the blood-brain barrier in non-human primates.
View Article and Find Full Text PDFDelivering genes to and across the brain vasculature efficiently and specifically across species remains a critical challenge for addressing neurological diseases. We have evolved adeno-associated virus (AAV9) capsids into vectors that transduce brain endothelial cells specifically and efficiently following systemic administration in wild-type mice with diverse genetic backgrounds, and in rats. These AAVs also exhibit superior transduction of the CNS across non-human primates (marmosets and rhesus macaques), and in ex vivo human brain slices, although the endothelial tropism is not conserved across species.
View Article and Find Full Text PDFThe blood-brain barrier (BBB) presents a major challenge for delivering large molecules to study and treat the central nervous system. This is due in part to the scarcity of targets known to mediate BBB crossing. To identify novel targets, we leverage a panel of adeno-associated viruses (AAVs) previously identified through mechanism-agnostic directed evolution for improved BBB transcytosis.
View Article and Find Full Text PDFAdeno-associated viruses (AAVs) promise robust gene delivery to the brain through non-invasive, intravenous delivery. However, unlike in rodents, few neurotropic AAVs efficiently cross the blood-brain barrier in non-human primates (NHPs). Here we describe AAV.
View Article and Find Full Text PDFCuO /TiO co-photocatalysts with various Cu loading contents were synthesized by an impregnation method, and their photocatalytic activities were evaluated by photodegradation of organic pollutants under visible light illumination. The as-prepared CuO /TiO composites exhibited a unique structure, in which CuO clusters with about 2-3 nm nanocrystals were uniformly distributed on the TiO cube. The mesoporous Ti/TiO substrate with a uniform pore structure greatly improved the uniformity of the loaded Cu, wherein Ti acted as a reducing agent for reducing Cu to Cu and Cu.
View Article and Find Full Text PDFHeavy metals such as cadmium (Cd) in farmland soil not only affect crop production, but also endanger human health through the food chain. Rice is the main food crop with the strongest ability to absorb Cd, remediation techniques to reduce soil uptake and grain accumulation of Cd are urgently required, for which the application of foliar spraying seems to be a convenient and auspicious method. This study clarified the effects of nitrogen (N), zinc (Zn), 24-epibrassionlide (EBL) and their combined application on the growth performance and physiological characteristics of Cd and Zn in rice plants under Cd stress.
View Article and Find Full Text PDFis a relative of wheat ( L.) with many disease resistance genes that can be used to improve wheat disease resistance. In order to enrich the germplasm resources available in wheat genetics and breeding, we assessed head blight (FHB) resistance in 45 interspecific derivatives between wheat and during two years from 2017-2018.
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