Prognostic value of RRM1 and its effect on chemoresistance in pancreatic cancer.

Purpose: Pancreatic cancer (PC) remains a lethal disease, and gemcitabine resistance is prevalent. However, the biomarkers suggestive of gemcitabine resistance remain unclear.

Methods: Bioinformatic tools identified ribonucleotide reductase catalytic subunit M1 (RRM1) in gemcitabine-related datasets.

Arsenic trioxide sensitizes pancreatic cancer cells to gemcitabine through downregulation of the TIMP1/PI3K/AKT/mTOR axis.

Gemcitabine (GEM) is the first-line medication for pancreatic ductal adenocarcinoma (PDAC). However, over some treatment cycles, GEM sensitivity declines and chemotherapeutic resistance develops, resulting in tumor recurrence and metastasis. Therefore, it is critical to elucidate the mechanism of GEM chemoresistance.

TIMP1 derived from pancreatic cancer cells stimulates Schwann cells and promotes the occurrence of perineural invasion.

Perineural invasion (PNI) occurs in most pancreatic ductal adenocarcinomas (PDACs). The relationship between cancer cells and peripheral nerves, however, is unknown. Therefore, we focused on the cooperation of PDAC cells and peripheral nerve astrocytes, Schwann cells (SCs), in PNI.

Mg-Al hydrotalcite-supported Pd catalyst for low-temperature CO oxidation: effect of Pd species and surface hydroxyl groups.

Hydrotalcite-like compounds (HTlcs) are promising supports or catalyst precursors for heterogeneous catalysts. Herein, MgAl-HTlcs-supported Pd catalyst was fabricated, and two Pd catalysts supported on Mg(OH)2 and Al(OH)3 were prepared for comparison. The presence of hydroxyl groups (OH-) in the support is important for obtaining uniform Pd nanoparticles with small sizes.

Cu/CeO Catalyst for Water-Gas Shift Reaction: Effect of CeO Pretreatment.

CuO/CeO is a kind of promising catalysts for the water-gas shift (WGS) reaction. Efforts were put in to improve its performance through modification of CeO support. In this study, portions of CeO prepared by a co-precipitation method were separately annealed at 300 °C in air, under vacuum and with H , and were used as supports for the fabrication of CuO/CeO catalysts.

Enhanced Raman scattering and photocatalytic activity of Ag/ZnO heterojunction nanocrystals.

In this work, we study the enhancement of Raman signals and photocatalytic activity of Ag/ZnO heterojunctions with an Ag content of 1 at.%, which were synthesized by photochemical deposition of Ag nanoparticles onto pre-synthesized ZnO nanorods. A strong interaction between Ag and ZnO nanocrystals were evidenced by XPS and UV-vis spectroscopy.

[Studies on Ag-TiO2/KIT-6 composite nanosized photocatalyst].

In the present paper, ordered mesoporous silica (KIT-6) as support, nanosized TiO2 into KIT-6 was synthesized by titanium tetraisopropoxide hydrolysis. Then silver was loaded by deposition-precipitation method. Ag-TiO2/KIT-6 composite nanosized photocatalyst was firstly synthesized and a series of correlated catalysts were synthesized by the same preparation method.

Network structured SnO2/ZnO heterojunction nanocatalyst with high photocatalytic activity.

A network-structured SnO(2)/ZnO heterojunction nanocatalyst with high photocatalytic activity was successfully synthesized through a simple two-step solvothermal method. The as-synthesized samples are characterized by X-ray diffraction, X-ray photoelectron spectroscopy, transmission electron microscopy, scanning electron microscopy, N(2) physical adsorption, and UV-vis spectroscopy. The results show that the SnO(2)/ZnO sample with a molar ratio of Sn/Zn = 1 is a mesoporous composite material composed of SnO(2) and ZnO.

[Study on the spectra of Au/CeO2 catalysts modified by La2O3 additive].

For Au-ceria catalysts prepared by deposition-precipitation method, the catalytic performance of water gas shift reaction was studied with different La loadings. In the complete doping range, ceria retains with its cubic fluorite structures. XRD, HRTEM and UV-Vis-DRS, studies showed that La doping can improve the activity of Au-ceria catalyst by stabilizing ceria and modifying its morphology.

Ag/ZnO heterostructure nanocrystals: synthesis, characterization, and photocatalysis.

A high yield of the dimer-type heterostructure of Ag/ZnO nanocrystals with different Ag contents is successfully prepared through a simple solvothermal method in the absence of surfactants. The samples are characterized by X-ray diffraction, transmission electron microscopy, X-ray photoelectron spectroscopy, UV-vis spectroscopy, and IR spectroscopy. The results show that all samples are composed of metallic Ag and ZnO; Ag nanoparticles locate on the surface of ZnO nanorods; the binding energy of Ag 3d(5/2) for the Ag/ZnO sample with a Ag content of 5.

Luminescence and photocatalytic activity of ZnO nanocrystals: correlation between structure and property.

Low-dimensional ZnO nanocrystals with controlled size, aspect ratio, and oxygen defects (e.g., type and concentration) are successfully prepared through simple solvothermal and thermal treatment methods.

[Study on the spectra of Au/alpha-Fe2O3 catalysts modified by ZrO2 and Nb2O5 promoters].

A series of Au/alpha-Fe2O3 catalysts promoted with ZrO2 and Nb2O5 were prepared by parallel co-precipitation method. Detailed characterizations were conducted by techniques including UV-Vis-DRS, XPS, TEM and XRF. Results indicated that the enrichment of Au, ZrO2 and Nb2O5 on the surface induced by the strong interaction between ZrO2 and Nb2O5 kept the nanoparticles apart, delaying sintering.