Aluminum scandium nitride on 8-inch Si wafers: material characterization and photonic device demonstration.

The anisotropic optical properties of aluminum scandium nitride (AlScxN) thin films for both ordinary and extraordinary light are investigated. A quantitative analysis of the band structures of the wurtzite AlScxN is carried out. In addition, AlScxN photonic waveguides and bends are fabricated on 8-inch Si substrates.

All-silicon metalens for broadband achromatic polarization multiplexing in long-wave infrared wavelengths.

Traditional long-wave infrared polarimetry usually relies on complex optical setups, making it challenging to meet the increasing demand for system miniaturization. To address this problem, we design an all-silicon broadband achromatic polarization-multiplexing metalens (BAPM) operating at the wavelength range of 9-12 µm. A machine-learning-based design method is developed to replace the tedious and computationally intensive simulation of a large number of meta-atoms.

Waveguide-integrated van der Waals heterostructure photodetector on a lithium niobate on insulator platform.

Lithium niobate (LN) photonics has gained significant interest for their distinct material properties. However, achieving monolithically integrated photodetectors on lithium niobate on an insulator (LNOI) platform for communication wavelengths remains a challenge due to the large bandgap and extremely low electrical conductivity of LN material. A two-dimensional (2D) material photodetector is an ideal solution for LNOI photonics with a strong light-matter interaction and simple integration technique.

Nanoimprinted TiO Metasurfaces with Reduced Meta-Atom Aspect Ratio and Enhanced Performance for Holographic Imaging.

Metasurface holograms, with the capability to manipulate spatial light amplitudes and phases, are considered next-generation solutions for holographic imaging. However, conventional fabrication approaches for meta-atoms are heavily dependent on electron-beam lithography (EBL), a technique known for its expensive and time-consuming nature. In this paper, a polarization-insensitive metasurface hologram is proposed using a cost-effective and rapid nanoimprinting method with titanium dioxide (TiO) nanoparticle loaded polymer (NLP).

Non-uniform distributed silicon optical phased array for high directionality and a wide steering range.

A non-uniform distributed silicon optical phased array (OPA) is proposed and numerically demonstrated to realize high directionality and a wide range for beam steering. The OPA is composed of grating antennas with dual-layer corrugations along silicon strip waveguides, which can achieve a high directionality of 0.96 and a small divergence angle of 0.

Mid-infrared integrated electro-optic modulators: a review.

Integrated mid-infrared (MIR) photonics have various applications in optical fiber communication, spectral detection and identification, free-space communication, and light detection and ranging, etc. The MIR electro-optic (EO) modulator, which is one of the key components of MIR integrated photonic systems, has attracted a lot of research interests. In this paper, we review the reported integrated MIR EO modulators based on different modulation mechanisms and material platforms.

Tunable slow and fast light in a silicon-on-insulator Fano resonator.

Tunable slow and fast light generation in a silicon-on-insulator (SOI) Fano resonator is proposed and experimentally demonstrated. The slow and fast light generation with symmetric and asymmetric coupling conditions of the Fano resonator is theoretically analyzed. Under a slightly imbalanced coupling condition, the two output ports of the Fano resonator could produce a fast light and a slow light, respectively.

[Hesperidin Regulates Jagged1/Notch1 Pathway to Promote Macrophage Polarization and Alleviate Lung Injury in Mice with Bronchiolitis].

Objective To explore the effect and mechanism of hesperidin in treating the lung injury in the mouse model of respiratory syncytial virus (RSV)-induced bronchiolitis. Methods A mouse model of RSV-induced bronchiolitis was established,and 60 BALB/c mice were assigned into a control group,a model group,a low-dose hesperidin (18 mg/kg) group,a high-dose hesperidin (36 mg/kg) group,and a high-dose hesperidin (36 mg/kg)+Jagged1(1 mg/kg) group by random number table method,with 12 mice in each group. Corresponding doses of drugs were administrated for intervention,and the control group and model group were administrated with the same amount of saline.

[Features of intestinal flora in children with food protein-induced proctocolitis based on high-throughput sequencing].

Objectives: To study the features of intestinal flora in children with food protein-induced proctocolitis (FPIP) by high-throughput sequencing.

Methods: A total of 31 children, aged <6 months, who experienced FPIP after exclusive breastfeeding and attended the outpatient service of the Third Affiliated Hospital of Zunyi Medical University from October 2018 to February 2021 were enrolled as the FPIP group. Thirty-one healthy infants were enrolled as the control group.

Cryogenically probing the surface trap states of single nanowires passivated with self-assembled molecular monolayers.

Optoelectronically probing the trap state density of single nanoscale devices is a powerful in situ nondestructive technique that is of significance for developing high gain photoconductors by surface engineering. However, the previously demonstrated optoelectronic methods are based on the exponential transient photoresponse assumption and only trap states in a very narrow bandgap region can be probed. In this Letter, we demonstrate a cryogenic technique that is capable of measuring the density of surface trap states in the full half bandgap without the exponential transient photoresponse assumption.

Electrospun homogeneous silk fibroin/poly (ɛ-caprolactone) nanofibrous scaffolds by addition of acetic acid for tissue engineering.

In this study, we investigated the phase separation phenomenon of silk fibroin/poly (ɛ-caprolactone) electrospinning solution to improve the performance of silk fibroin/poly (ɛ-caprolactone) electrospun nanofibers. It showed that phase separation does occur in just a few hours in the silk fibroin/poly (ɛ-caprolactone)/formic acid mixture solution. Acetic acid, small molecule nonsolvent for silk fibroin, was first introduced to silk fibroin/poly (ɛ-caprolactone)/formic acid solution, a homogeneous solution without separation for over several days was achieved after mixing for 5 h.

Identification of Pseudomonas aeruginosa genes associated with antibiotic susceptibility.

Pseudomonas aeruginosa causes acute and chronic infections in humans and these infections are difficult to treat due to the bacteria's high-level of intrinsic and acquired resistance to antibiotics. To address this problem, it is crucial to investigate the molecular mechanisms of antibiotic resistance in this organism. In this study, a P.

[Screen and identification of genes involved in multidrug resistance in Pseudomonas aeruginosa].

Objective: To identify genes involved in multidrug resistance in Pseudomonas aeruginosa.

Methods: We constructed and screened a transposon mutation library and obtained mutants that exhibited decreased drug resistance. The insertion sites of the transposon were identified by arbitrary PCR and subsequent DNA sequencing.