Publications by authors named "Xingwen Hu"

To analyze changes in the detection of parainfluenza virus (PIV) in children hospitalized with acute respiratory tract infection (ARTI) during 2014-2022 in Hubei Province, and explore the impact of the universal two-child policy and the public health measures against COVID-19 epidemic on the prevalence of PIV in China. The study was conducted at the Maternal and Child Health Hospital of Hubei Province. Children aged <18 years with ARTI admitted from January 2014 to June 2022 were enrolled.

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Article Synopsis
  • - The study examines how the universal two-child policy in China affected the rates of Influenza virus (IFV) infections among hospitalized children with acute respiratory tract infections (ARTI) from 2014 to 2022.
  • - Findings show that the IFV positive rate increased significantly after the policy's implementation, particularly among children under one year, reaching a peak in 2019, but dropped sharply during the initial COVID-19 outbreak.
  • - The results highlight a shift in the epidemiological patterns of IFV infections and suggest the need for future research on the health impacts of public health measures regarding COVID-19 on IFV transmission.
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Article Synopsis
  • - The study examined the dynamics of respiratory syncytial virus (RSV) among hospitalized children with acute respiratory tract infections in Hubei Province from 2014 to 2022, highlighting a lack of longitudinal data on the virus in the region.
  • - Results indicated that RSV was detected in 11.1% of hospitalized children, with higher rates in infants under 1 year old, and those with lower respiratory tract infections, showing a pronounced seasonal pattern peaking between December and February.
  • - The research also assessed the effects of China's 2-child policy and the COVID-19 pandemic on RSV prevalence, using statistical models to analyze changes in detection rates before and after these events.
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Background: Few studies have investigated the association of maternal longitudinal hemoglobin (Hb) with small for gestational age during pregnancy. The current study examined the associations of maternal Hb concentrations and Hb changes throughout the middle and late stages of pregnancy with small for gestational age (SGA) in a large prospective cohort study. Methods: This was a prospective cohort study, which enrolled pregnant women at 8−16 weeks of gestation and followed up regularly.

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Flat-top beams have plenty of applications in theoretical and applied research, but they are not eigenmodes of the wave equation. Here, we propose an effective strategy for generating flat-top beams in fibers, which originates from the incoherent superposition of orbital angular momentum (OAM) and fundamental (LP) modes. The designed all-fiber passively Q-switched laser can realize high-quality pulsed flat-top and OAM beam emissions.

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Objective: To investigate the association of the maternal serum albumin (MAlb) level with fetal growth and fetal growth restriction (FGR) risk in term-born singletons.

Design: Prospective cohort study.

Setting: Four hospital maternity units of the Tongji Maternal and Child Health Cohort study initiated from September 2013 to April 2016 at Wuhan City, in central China.

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We aimed to assess protein nutrition status during pregnancy by maternal plasma total protein (MTP) levels in urban pregnant women and to explore the association between the trimester-specific MTP levels and risk of preterm birth (PTB). A prospective design was conducted in 3,382 mother-newborn pairs with the second-trimester maternal MTP information and in 3,478 mother-newborn pairs with the third-trimester MTP information. Multiple Cox proportional hazard regression and multiple linear regression were used to analyse the associations between MTP levels and PTB risk as well as gestational duration, respectively.

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Purpose: Emerging clinical evidence has implied that alkaline phosphatase (ALP) may contribute to gestational diabetes mellitus (GDM). However, there were no studies to reveal the independent and prospective associations between ALP and GDM. Our aim was to explore the independent and prospective associations between early maternal ALP level and GDM risk and glucose regulation.

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Background & Aims: Oxidative stress has been implicated in the pathogenesis of gestational diabetes mellitus (GDM). Vitamin C as natural antioxidant may help to increase the body's antioxidant capacity. The study is aimed to determine whether vitamin C intake during pregnancy is associated with lower risk of GDM.

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Bilirubin concentrations have been recently reported to be negatively associated with type 2 diabetes mellitus. We examined the association between bilirubin concentrations and gestational diabetes mellitus. In a prospective cohort study, 2969 pregnant women were recruited prior to 16 weeks of gestation and were followed up until delivery.

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Evidence has been presented that the species currently known as Ureaplasma urealyticum should be separated into 2 species-Ureaplasma parvum (previously, U. urealyticum biovar 1) and U. urealyticum (previously, U.

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