Publications by authors named "Xingtong Chen"

Objectives: We aimed to evaluate the analytical performance of second-trimester maternal serum screening in China, and to compare if there are differences in sigma levels across different methods and months.

Methods: A retrospective study was conducted to assess the analytical quality levels of laboratories by calculating the Sigma metrics with prenatal screening biomarkers: AFP, Total β-hCG, free β-hCG, uE3. Data from 591 laboratories were selected.

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The existing methods to improve the charge balance of quantum dot light-emitting diodes (QLEDs) rely on energy-level matching, but these approaches have been limited by material availability and Fermi-level pinning. Here, we propose a solution that does not require changes to the materials' electronic properties. By using nanoimprinting technology to texture the interface between the hole-transporting layer (HTL) and colloidal quantum dot (CQD) layer, we can increase the HTL-CQD contact area.

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Top emission can enhance luminance, color purity, and panel-manufacturing compatibility for emissive displays. Still, top-emitting quantum-dot light-emitting diodes (QLEDs) suffer from poor stability, low light outcoupling, and non-negligible viewing-angle dependence because, for QLEDs with non-red emission, the electrically optimum device structure is incompatible with single-mode optical microcavity. Here, we demonstrate that by improving the way of determining reflection penetration depths and creating refractive-index-lowering processes, the issues faced by green QLEDs can be overcome.

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Background: Dexmedetomidine (Dex) may have anti-inflammatory properties and potentially reduce the incidence of postoperative organ injury.

Objective: To investigate whether Dex protects pulmonary and renal function via its anti-inflammatory effects in elderly patients undergoing prolonged major hepatobiliary and pancreatic surgery.

Design And Setting: Between October 2019 and December 2020, this randomized controlled trial was carried out at a tertiary hospital in Chongqing, China.

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The traditional prescription of Liangxue-Qushi-Zhiyang decoction (LQZ) has been demonstrated to be efficacious in treating atopic dermatitis (AD), a chronic inflammatory skin disorder marked by intense itching, redness, rashes, and skin thickening. Nevertheless, there has been an inadequate systematic exploration of the potential targets, biological processes, and pathways for AD treatment through LQZ. The study objective was to evaluate the efficacy and possible mechanism of LQZ in AD mice.

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Aberrant mRNA expression is implicated in uterine corpus endometrial carcinoma (UCEC) oncogenesis and progression. However, effective prognostic biomarkers for UCEC remain limited. We aimed to construct a reliable multi-gene risk model using gene expression profiles.

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The urgent concerns of controlling water body eutrophication and the alleviating phosphorus shortage have led to an urgent need for action. The removal of phosphate from polluted waters and its reuse are essential for the prevention of eutrophication and for the sustainable utilization of phosphate resources. In this study, modified attapulgite with different Ca:Mg molar ratios was synthesized to facilitate the recovery of phosphate, with subsequent use of soil fertilizer.

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Inefficient hole injection presents a major challenge in achieving stable and commercially viable solution-processed blue electroluminescent devices. Here, we conduct an in-depth study on quantum-dot light-emitting diodes (QLEDs) to understand how the energy levels of common electrodes and hole-transporting layers (HTL) affect device degradation. Our experimental findings reveal a design rule that may seem nonintuitive: combining an electrode and HTL with matched energy levels is most effective in preventing voltage rise and irreversible luminance decay, even though it causes a significant energy offset between the HTL and emissive quantum dots.

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A front surface gradient of the absorber valence band can effectively reduce the open-circuit voltage (V) loss of perovskite solar cells by suppressing the minority carrier concentration near the front surface. However, the existing method is limited to the one-step fabrication process, resulting in underachieved photon harvesting and power conversion efficiency (PCE). To solve the problem, ZnCd-based alloy quantum dots (QDs) are utilized to create a valence-band-maximum gradient at the front surface of a two-step processed FAPbI absorber.

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Article Synopsis
  • * The existing blue quantum dots achieve high efficiency but suffer from significant surface-bulk coupling, limiting their operational lifespan due to localized charges affecting performance.
  • * A novel approach using blue quantum dots with a modified core-shell structure helps reduce this coupling, allowing for a range of emission colors and improved operational lifetimes of 75 to 227 hours, surpassing previous benchmarks.
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Digitization offers fresh impetus to the transformation and upgrading of mining enterprises, while on the other hand, the rapid development and broad application of digital technologies make the environmental governance of mining enterprises the most important themes of theoretical research and practical exploration. In this paper, A-share companies listed between 2007 and 2020 are taken as samples to study the influence of digital transformation on the environmental governance of mining enterprises, and its relative acting paths. Our main research methods are multiple linear regression analysis, the panel fixed-effect model and the intermediary effect model.

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Objective: To investigate the effects of different general anesthesia methods on the changes of serum hepatitis B virus deoxyribonucleic acid (HBV-DNA) levels in the hepatitis B virus (HBV) infected patients.

Methods: This pilot prospective observational study was carried out from March 2021 to January 2022. Forty patients infected by HBV, who underwent non-hepatobiliary minimally invasive surgery, were allocated into an intravenous anesthesia group maintained with propofol (Group P, n = 20) and an inhalation anesthesia group maintained with sevoflurane (Group S, n = 20) by a random envelope method.

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ZnO-based electron-transporting layers (ETLs) have been universally used in quantum-dot light-emitting diodes (QLEDs) for high performance. The active surface chemistry of ZnO nanoparticles (NPs), however, leads to QLEDs with positive aging and unacceptably poor shelf stability. SnO is a promising candidate for ETLs with less reactivity, but NP agglomeration in nonionic solvents makes the conventional device structure abandoned, resulting in QLEDs with extremely low operational lifetimes.

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For organic solar cells (OSCs), the charge generation mechanism and the recombination loss are heavily linked with charge transfer states (CTS). Measuring the energy of CTS () by the most widely used technique, however, has become challenging for the non-fullerene-based OSCs with a small driving force, resulting in difficulty in the understanding of OSC physics. Herein, we present a study of the PM6:Y6 bulk heterojunction.

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Background: Blood pressure fluctuation is very common during non-cardiac surgery in elderly. This retrospective study was to analyse whether intraoperative hypotension in elderly and other risk factors relate to the postoperative mortality.

Methods: A total of 118 cases (Observational group), who underwent noncardiac surgery in three medical centers between September 2014 and March 2017, and died in the hospital after the noncardiac surgery.

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All-inorganic perovskite quantum dots (PQDs), potentially applicable to high-performance display technologies, are facing challenges when the superior luminescence properties with high stability and uncompromised electrical conductivity are combined. Here, by introducing hexylamine sulfate and reducing the reaction rate, we managed to optimize the surface sacrificial coating of CsPbBr QDs. As a result, the colloidal PQDs show a photoluminescence quantum efficiency (PLQE) of 95.

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Aims: This study aims to evaluate the effects of dexmedetomidine on organ function, inflammation response, and oxidative stress in elderly patients following iatrogenic lower limb ischaemia-reperfusion (IR) during unilateral total knee arthroplasty.

Methods: Following unilateral total knee arthroplasty, 54 elderly patients were randomized to receive either intraoperative intravenous injection of dexmedetomidine (n = 27) or equivalent volume of 0.9% saline (n = 27).

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For quantum-dot photodiodes comprising an electron-transporting layer assembled of ZnO nanoparticles, the light emitter/absorber generally exhibits enhanced optoelectronic performance after the device is shelf-aged. To understand the so-called positive aging effect, the optoelectronic properties of ZnO nanoparticles are investigated at the thin film and device level as a function of aging time. It is evidenced that the aging process is driven by a surface-stabilizing mechanism of ZnO nanoparticles, in which the active surface adsorption sites for oxygen are gradually but irreversibly stabilized, i.

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In this work, polyurethane sponge is employed as the structural substrate of the sensor. Graphene oxide (GO) and polypyrrole (PPy) are alternately coated on the sponge fiber skeleton by charge layer-by-layer assembly (LBL) to form a multilayer composite conductive layer to prepare the piezoresistive sensors. The 2D GO sheet is helpful for the formation of the GO layers, and separating the PPy layer.

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In this work, a piezoresistive sensor structure based on carbon black (CB)@polyurethane (PU) yarn material was developed. Specifically, CB@PU yarn was constructed by the polymer-mediated water-based electrostatic deposition method. The distribution of the yarn was artificially controlled to fabricate conductive networks.

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Indoor dust was an important and even a major route of human exposure to polybrominated diphenyl ethers (PBDEs). However, the vacuum dust concentrations were less correlated with indoor residents' serum concentrations of PBDEs, thus inadequat for either estimation of human exposure dose or research of deposition flux and its seasonal variations. Passive sampling of indoo dustfall could offset these shortages.

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DNA is a valid drug target for development of target-based therapeutics against cancer. Screening DNA-targeted anticancer drugs is a key process for the research and development of new anticancer drugs. The traditional anticancer drug screening methods, including animal experiments and cell-based screening assays, have unavoidable drawbacks.

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