Publications by authors named "Xingrui Yan"
Background: A vicious cycle of dysregulated intestinal epithelial cell death, intestinal barrier defect, and subsequent inflammation response is core to chronic ulcerative colitis (UC). Modified Jiaoqi Powder (MJQP), a traditional Chinese medicine formula, has been clinically applied to treat chronic relapsing and chronic persistent types of UC. Nevertheless, the underlying mechanisms of MJQP in chronic UC remains unknown.
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- Periodontitis is an inflammatory disease caused by dental plaque that can lead to tooth loss, necessitating treatments that focus on reducing bone loss through antibacterial and anti-inflammatory measures.
- Injectable hydrogels, made from natural and synthetic materials, have gained attention for their ability to deliver drugs effectively, due to their compatibility and ease of use.
- The review covers different types of hydrogels based on their raw materials, cross-linking methods, and stimuli-responsive capabilities, while highlighting the current challenges and potential for clinical use in periodontitis treatment.
Ethnopharmacological Relevance: Paris polyphylla Sm. (P.P), is a widely-used traditional Chinese medicine (TCM) in the treatment of wound, throat sores and snakebites.
View Article and Find Full Text PDFBackground: Gastric cancer (GC), an extremely aggressive tumor with a very different prognosis, is the third leading cause of cancer-related mortality. We aimed to construct a ferroptosis-related prognostic model that can be distinguished prognostically.
Methods: The gene expression and the clinical data of GC patients were downloaded from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus database (GEO).