Optical Coherence Tomography (OCT) facilitates a comprehensive examination of macular edema and associated lesions. Manual delineation of retinal fluid is labor-intensive and error-prone, necessitating an automated diagnostic and therapeutic planning mechanism. Conventional supervised learning models are hindered by dataset limitations, while Transformer-based large vision models exhibit challenges in medical image segmentation, particularly in detecting small, subtle lesions in OCT images.
View Article and Find Full Text PDFComput Struct Biotechnol J
December 2024
This paper presents an improved genetic algorithm focused on multi-threshold optimization for image segmentation in digital pathology. By innovatively enhancing the selection mechanism and crossover operation, the limitations of traditional genetic algorithms are effectively addressed, significantly improving both segmentation accuracy and computational efficiency. Experimental results demonstrate that the improved genetic algorithm achieves the best balance between precision and recall within the threshold range of 0.
View Article and Find Full Text PDFBackground: Prominent epicanthus could not only diminish the eyes' aesthetics but may be deceptive for its typical appearance of pseudo-esotropia. This study aims to apply a deep learning model to characterize the periocular morphology for preliminary identification.
Methods: This prospective study consecutively included 300 subjects visiting the ophthalmology department in a tertiary referral hospital.
The incorporation of automatic segmentation methodologies into dental X-ray images refined the paradigms of clinical diagnostics and therapeutic planning by facilitating meticulous, pixel-level articulation of both dental structures and proximate tissues. This underpins the pillars of early pathological detection and meticulous disease progression monitoring. Nonetheless, conventional segmentation frameworks often encounter significant setbacks attributable to the intrinsic limitations of X-ray imaging, including compromised image fidelity, obscured delineation of structural boundaries, and the intricate anatomical structures of dental constituents such as pulp, enamel, and dentin.
View Article and Find Full Text PDFIEEE Trans Med Imaging
August 2024
Ophthalmic diseases such as central serous chorioretinopathy (CSC) significantly impair the vision of millions of people globally. Precise segmentation of choroid and macular edema is critical for diagnosing and treating these conditions. However, existing 3D medical image segmentation methods often fall short due to the heterogeneous nature and blurry features of these conditions, compounded by medical image clarity issues and noise interference arising from equipment and environmental limitations.
View Article and Find Full Text PDFThe thickness of the choroid is considered to be an important indicator of clinical diagnosis. Therefore, accurate choroid segmentation in retinal OCT images is crucial for monitoring various ophthalmic diseases. However, this is still challenging due to the blurry boundaries and interference from other lesions.
View Article and Find Full Text PDFOptical coherence tomography angiography (OCTA) offers critical insights into the retinal vascular system, yet its full potential is hindered by challenges in precise image segmentation. Current methodologies struggle with imaging artifacts and clarity issues, particularly under low-light conditions and when using various high-speed CMOS sensors. These challenges are particularly pronounced when diagnosing and classifying diseases such as branch vein occlusion (BVO).
View Article and Find Full Text PDFMacular holes, one of the most common macular diseases, require timely treatment. The morphological changes on optical coherence tomography (OCT) images provided an opportunity for direct observation of the disease, and accurate segmentation was needed to identify and quantify the lesions. Developments of such algorithms had been obstructed by a lack of high-quality datasets (the OCT images and the corresponding gold standard macular hole segmentation labels), especially for supervised learning-based segmentation algorithms.
View Article and Find Full Text PDFIntroduction: Changes in coronary artery luminal dimensions during the cardiac cycle can impact the accurate quantification of volumetric analyses in intravascular ultrasound (IVUS) image studies. Accurate ED-frame detection is pivotal for guiding interventional decisions, optimizing therapeutic interventions, and ensuring standardized volumetric analysis in research studies. Images acquired at different phases of the cardiac cycle may also lead to inaccurate quantification of atheroma volume due to the longitudinal motion of the catheter in relation to the vessel.
View Article and Find Full Text PDFSensors (Basel)
September 2023
This paper designs a fast image-based indoor localization method based on an anchor control network (FILNet) to improve localization accuracy and shorten the duration of feature matching. Particularly, two stages are developed for the proposed algorithm. The offline stage is to construct an anchor feature fingerprint database based on the concept of an anchor control network.
View Article and Find Full Text PDFAutomated retinal blood vessel segmentation in fundus images provides important evidence to ophthalmologists in coping with prevalent ocular diseases in an efficient and non-invasive way. However, segmenting blood vessels in fundus images is a challenging task, due to the high variety in scale and appearance of blood vessels and the high similarity in visual features between the lesions and retinal vascular. Inspired by the way that the visual cortex adaptively responds to the type of stimulus, we propose a Stimulus-Guided Adaptive Transformer Network (SGAT-Net) for accurate retinal blood vessel segmentation.
View Article and Find Full Text PDFIntravascular ultrasound (IVUS) is recommended in guiding coronary intervention. The segmentation of coronary lumen and external elastic membrane (EEM) borders in IVUS images is a key step, but the manual process is time-consuming and error-prone, and suffers from inter-observer variability. In this paper, we propose a novel perceptual organisation-aware selective transformer framework that can achieve accurate and robust segmentation of the vessel walls in IVUS images.
View Article and Find Full Text PDFBackground: Myopic traction maculopathy (MTM) are retinal disorder caused by traction force on the macula, which can lead to varying degrees of vision loss in eyes with high myopia. Optical coherence tomography (OCT) is an effective imaging technique for diagnosing, detecting and classifying retinopathy. MTM has been classified into different patterns by OCT, corresponding to different clinical strategies.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
January 2024
Deep learning methods are frequently used in segmenting histopathology images with high-quality annotations nowadays. Compared with well-annotated data, coarse, scribbling-like labelling is more cost-effective and easier to obtain in clinical practice. The coarse annotations provide limited supervision, so employing them directly for segmentation network training remains challenging.
View Article and Find Full Text PDFWhen dentists see pediatric patients with more complex tooth development than adults during tooth replacement, they need to manually determine the patient's disease with the help of preoperative dental panoramic radiographs. To the best of our knowledge, there is no international public dataset for children's teeth and only a few datasets for adults' teeth, which limits the development of deep learning algorithms for segmenting teeth and automatically analyzing diseases. Therefore, we collected dental panoramic radiographs and cases from 106 pediatric patients aged 2 to 13 years old, and with the help of the efficient and intelligent interactive segmentation annotation software EISeg (Efficient Interactive Segmentation) and the image annotation software LabelMe.
View Article and Find Full Text PDFQuant Imaging Med Surg
March 2023
Background: We aimed to propose a deep learning-based approach to automatically measure eyelid morphology in patients with thyroid-associated ophthalmopathy (TAO).
Methods: This prospective study consecutively included 74 eyes of patients with TAO and 74 eyes of healthy volunteers visiting the ophthalmology department in a tertiary hospital. Patients diagnosed as TAO and healthy volunteers who were age- and gender-matched met the eligibility criteria for recruitment.
Eyelid tumors are tumors that occur in the eye and its appendages, affecting vision and appearance, causing blindness and disability, and some having a high lethality rate. Pathological images of eyelid tumors are characterized by large pixels, multiple scales, and similar features. Solving the problem of difficult and time-consuming fine-grained classification of pathological images is important to improve the efficiency and quality of pathological diagnosis.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2023
Background: Inferior oblique overaction (IOOA) is a common ocular motility disorder. This study aimed to propose a novel deep learning-based approach to automatically evaluate the amount of IOOA.
Methods: This prospective study included 106 eyes of 72 consecutive patients attending the strabismus clinic in a tertiary referral hospital.
Purpose: To automatically predict the postoperative appearance of blepharoptosis surgeries and evaluate the generated images both objectively and subjectively in a clinical setting.
Design: Cross-sectional study.
Participants: This study involved 970 pairs of images of 450 eyes from 362 patients undergoing blepharoptosis surgeries at our oculoplastic clinic between June 2016 and April 2021.
Objective: To analyze the application effect of Jiawei Sanyu Shengjing decoction combined with high ligation of the internal spermatic vein in male infertility patients with varicocele (VC).
Methods: 106 male infertility patients with VC treated in our hospital from December 2018 to March 2019 were selected as examples. According to the length of stay, they were divided into the control group and observation group, with 53 cases in each group.
Retinal vasculature provides an opportunity for direct observation of vessel morphology, which is linked to multiple clinical conditions. However, objective and quantitative interpretation of the retinal vasculature relies on precise vessel segmentation, which is time consuming and labor intensive. Artificial intelligence (AI) has demonstrated great promise in retinal vessel segmentation.
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