[Mouse bone marrow mesenchymal stem cells co-overexpressing IFN-γ/sPD-1 have high biological activity and genetic stability].

Objective To investigate the effects of lentivirus-mediated overexpression of interferon gamma (IFN-γ) and soluble programmed death 1 (sPD-1) on the biological activity and genetic stability of bone marrow mesenchymal stem cells (BMSCs). Methods BMSCs were isolated and cultured by whole bone marrow adhesion method. The expression of surface markers of BMSCs was identified by flow cytometry.

Bibliometric analysis of the research hotspots and trends of circular RNAs.

Background And Objective: Circular RNAs (circRNAs) have garnered considerable attention in the study of various human diseases due to their ubiquitous expression and potential biological functions. This study conducts a bibliometric and visualization-based analysis of circRNA-related research in diseases, aiming to reveal the current status, hotspots and emerging trends within the field.

Methods: Literature published between 2013 and 2022 and indexed in the Web of Science core databases was retrieved.