Publications by authors named "Xingmin Ning"
Article Synopsis
- Pyruvate dehydrogenase complex (PDC) is key for linking glycolysis to the TCA cycle, essential for converting pyruvate into acetyl CoA for energy production.
- PDC activity is influenced by various post-translational modifications (PTMs) like phosphorylation, acetylation, and O-GlcNAcylation, which impact its function in different health conditions.
- This review highlights how these PTMs relate to cardiovascular diseases (CVDs) such as heart failure and diabetic cardiomyopathy, suggesting their potential as targets for diagnostics and treatments.
