Application of an optimized interpretation model in capillary hemoglobin electrophoresis for newborn thalassemia screening.

Introduction: Newborn screening is an important supplement to thalassemia control and prevention. Capillary electrophoresis (CE) technology has several advantages for thalassemia screening but with low sensitivity, especially for thalassemia carriers. This study aims to illustrate the application of an optimized interpretation model in newborn thalassemia screening by capillary hemoglobin electrophoresis.

[Epidemiological analysis of selected congenital limb malformations in Hengyang].

Objective: To describe the epidemiological characteristics of selected congenital limb malformations (CLM) in newborns of Hengyang.

Methods: During the period of 2008-2010, cluster sampling survey was adopted to investigate the congenital limb malformations of neonates born to women resident in Hengyang, including Nanyue District, Zhuhui District, Changning City and Hengshan County. Each newborn was examined for the screening of CLM after birth.