Publications by authors named "Xinghe Pan"
Papillary thyroid carcinoma (PTC), the most common thyroid cancer, has been linked to various molecular alterations. This study focuses on microRNA-223-3p, whose upregulated expression in PTC tissues appears to enhance tumor growth and cellular dysfunctions. Our findings demonstrate that microRNA-223-3p significantly promotes cell proliferation, invasion, and migration and induces epithelial-mesenchymal transition (EMT).
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- * Researchers analyzed data from 5,497 adult patients with FLD, focusing on novel SI markers—systemic immune-inflammation index (SII), pan-immune-inflammation value (PIV), and systemic inflammation response index (SIRI)—to gauge their impact on mortality rates.
- * Findings show that SII and PIV are significantly linked to increased all-cause mortality rates in FLD patients, with PIV likely having a stronger connection to cardiovascular-related deaths.
Association between Life's Essential 8 and psoriasis in US adults: a cross-sectional study.
Front Med (Lausanne)
October 2024
Background: Psoriasis is closely associated with cardiovascular disease (CVD). However, the current evidence on the correlation between Life's Essential 8 and Psoriasis is insufficient. Our aim was to investigate the relationship between Life's Essential 8 (LE8), a measure of cardiovascular health (CVH), and psoriasis.
View Article and Find Full Text PDFDesmoid tumors of rectus abdominis: A case report and literature review.
Medicine (Baltimore)
July 2024
Rationale: Desmoid tumor (DT) is a rare soft tissue tumor that can occur anywhere in the body. Abdominal wall DT presents unique clinical challenges due to its distinctive manifestations, treatment modalities, and the lack of biomarkers for diagnosis and recurrence prediction, making clinical decisions exceedingly complex.
Patient Concerns: A 32-year-old female who underwent radical resection combined with patch reinforcement for rectus abdominis DT, successfully alleviating abdominal discomfort, with no recurrence during the 6-month follow-up after surgery.
Article Synopsis
- * CT scans confirmed a solid mass in the left kidney and associated metastasis, leading to treatment with axitinib and later tislelizumab after positive PD-1 expression was detected.
- * After 8 months of treatment, the patient's tumor significantly shrank, allowing for surgery, and 30 months post-treatment, she showed no signs of cancer recurrence or metastasis, indicating successful long-term survival.