Publications by authors named "Xinghe Huang"
Introduction: The integration of artificial intelligence (AI) in pathogenic microbiology has accelerated research and innovation. This study aims to explore the evolution and trends of AI applications in this domain, providing insights into how AI is transforming research and practice in pathogenic microbiology.
Methods: We employed bibliometric analysis and topic modeling to examine 27,420 publications from the Web of Science Core Collection, covering the period from 2010 to 2024.
Background: To explore the association of cardiovascular-kidney-metabolic (CKM) health with the risk of depression and anxiety and to investigate the joint association of CKM health and social connection with depression and anxiety.
Methods: This prospective cohort study included 344 956 participants from the UK Biobank. CKM syndrome was identified as a medical condition with the presence of metabolic risk factors, cardiovascular disease, and chronic kidney disease, and was classified into five stages (stage 0-4) in this study.
Background: The coexistence of cardiovascular disease and chronic kidney disease, termed chronic cardiovascular-kidney disorder (CCV-KD), is increasingly prevalent. However, limited studies have assessed the association between cardiovascular health (CVH), assessed by the American Heart Association's Life's Essential 8 (LE8), and CCV-KD.
Methods: We conducted a prospective cohort study using data from UK Biobank.
Association of Cardiovascular Health With Risk of Incident Depression and Anxiety.
Am J Geriatr Psychiatry
May 2024
Objective: To investigate the association between cardiovascular health (CVH), defined by the American Heart Association's Life's Essential 8 (LE8) score, and incident depression and anxiety.
Design: A prospective cohort study using data from UK Biobank.
Setting: Participants were enrolled from March 2006 to October 2010.
Background: Blood pressure (BP) is a dynamic measure that fluctuates over time. However, conventional BP control indicators may not adequately reflect the variability of BP during a period of time.
Methods: We performed a secondary analysis of the Systolic Blood Pressure Intervention Trial (SPRINT), which compared systolic blood pressure (SBP) targets of <120 mmHg (intensive) and <140 mmHg (standard) among patients with hypertension and high cardiac risks.
Objective: This systematic review aimed to examine the effects of motivational interviewing-based interventions on hypertension management.
Methods: Six databases were searched from inception to 25 July, 2022 for randomized controlled trials involving adults diagnosed with hypertension and including motivational interviewing in the treatment interventions.
Results: In total, 11 studies with 2121 participants were included.
Background: The effect of early exposure to famine on progression of depressive symptoms has not been studied and the Chinese Famine offers a unique opportunity to explore this association with its long duration and widespread influence.
Objective: To investigate the longitudinal association of early famine exposure with subsequent depressive symptoms and whether there existed a critical exposure period.
Methods: Data from the China Health and Retirement Longitudinal Study (CHARLS) were analysed.
Article Synopsis
- High systolic blood pressure (SBP) is linked to poor health outcomes in patients with heart failure (HF), and this study aimed to clarify how SBP affects long-term prognosis for those hospitalized with HF.
- Researchers included 4,564 adult patients from 52 hospitals in China and assessed SBP at discharge, tracking rates of 1-year all-cause death and HF readmission.
- Results showed that SBP levels below 110 mmHg and above 150 mmHg significantly increased risks for both death and readmission, indicating a J-curve relationship with optimal SBP around 130 mmHg.
Article Synopsis
- A study was conducted on hospitalized heart failure patients in China to evaluate how certain biomarkers can predict clinical outcomes and assess quality of life.
- The research involved 4,693 patients and utilized a multi-biomarker panel comprised of five specific indicators related to heart failure severity, and it linked these indicators to cardiovascular death and other health outcomes over one year.
- Results showed a relationship between the biomarker scores and mortality risk; higher scores indicated worse prospects, as patients in higher score groups had significantly worse health outcomes compared to those in the lowest score group.
Article Synopsis
- Heart failure with preserved ejection fraction (HFpEF) is a significant public health issue that lacks effective ways to assess patient risk.
- The study analyzed 18 biomarkers in 380 hospitalized patients to predict the 2-year risk of all-cause death, using techniques like Cox regression and a machine learning method called support vector machine (SVM).
- Results showed that certain biomarkers can effectively predict mortality risk, and the SVM model significantly improved patient classification over traditional methods, indicating its potential for better risk assessment in HFpEF.
Article Synopsis
- The study investigates the characteristics and management of valvular heart disease (VHD) in China, focusing on patient demographics, aetiology, and outcomes for those hospitalised in 2015.
- A national sample of 9,363 VHD patients was analyzed, revealing that the average age was 68.7 years, with degenerative conditions being the most common cause overall, while rheumatic origins were prevalent among those with primary VHD diagnoses.
- The findings highlight that mitral regurgitation was the most common type of VHD and that only 35.6% of patients with severe VHD required valve intervention in hospitals equipped for such procedures.
Objectives: This study aims to examine the association between the Kansas City Cardiomyopathy Questionnaire (KCCQ)-12 score and the 30-day and 1-year rates of composite events of cardiovascular death and heart failure (HF) rehospitalization in patients with acute HF.
Background: Few studies reported the prognostic effects of KCCQ in acute HF.
Methods: This study prospectively enrolled adult patients hospitalized for HF from 52 hospitals in China and collected the KCCQ-12 score within 48 hour of index admission.
Article Synopsis
- The study aimed to explore the link between admission systolic blood pressure (SBP) and one-year outcomes in heart failure patients hospitalized in China.
- It analyzed data from nearly 4,900 patients and found that lower admission SBP was linked to higher risks of both all-cause death and heart failure readmission, particularly when SBP was below 120 mmHg.
- These findings suggest that monitoring and managing admission SBP could be crucial for improving the prognosis of heart failure patients after hospitalization.
Introduction: China faces the prospect of a large growth in the prevalence of heart failure (HF). However, there is limited knowledge about outcomes in patients after HF hospitalisations, including patient-reported outcomes (PROs). This paper is to present the study goal, methodology and data collection of the China Patient-centred Evaluative Assessment of Cardiac Events Prospective Heart Failure Study (China PEACE 5p-HF Study).
View Article and Find Full Text PDFAims: Limited studies have been conducted to explore risk factors of developing multidrug-resistant tuberculosis (MDR-TB) in China. This study aimed to find the proportions and risk factors of developing MDR-TB in China among new patients and previously treated tuberculosis (TB) patients.
Methods: A population-based case-control study was conducted from March 2010 to December 2013 in five cities in China.