Publications by authors named "Xinghao Yi"
Article Synopsis
- The study investigates the connection between obesity and non-alcoholic fatty liver disease (NAFLD) in Chinese youth, focusing on how specific adipokines and hepatokines serve as potential links between the two conditions.
- Analysis was conducted on data from the Beijing Children and Adolescents Metabolic Syndrome (BCAMS) study, examining metabolic risks through ultrasound and plasma biomarker measurements to evaluate the obesity-NAFLD relationship.
- Results showed strong associations between elevated levels of RBP4, FGF21, and leptin, along with decreased adiponectin, as predictors of NAFLD, indicating that dysregulated adipokines/hepatokines play a significant role in the development of obesity-related NAFLD in young individuals
Background And Aims: Obesity is a chronic disease which can cause severe metabolic disorders. Machine learning (ML) techniques, especially deep learning (DL), have proven to be useful in obesity research. However, there is a dearth of systematic reviews of DL applications in obesity.
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- Sleep disorders, particularly sleep fragmentation (SF), are linked to increased risks of cardiovascular diseases, prompting research on how SF affects heart health across different life stages.
- A study using mouse models found that chronic SF negatively impacted heart function and structure, especially in early life, highlighting alterations in ventricular remodeling and contractile function.
- Gene analysis revealed key genes related to innate immune responses and circadian rhythms that are affected by SF; importantly, the negative impacts of SF on heart function were largely reversed with subsequent sleep recovery.
Tuberculosis (TB) is a severe infectious disease that seriously endangers human health. The immune defence mechanism of the body against TB is still unclear. The purpose of this study was to find the key molecules involved in the immune defence response during TB infection, and provide reference for the treatment of TB and further understanding of the immune defence mechanism of the body.
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