A nomogram combining prognostic nutritional index and platelet lymphocyte ratio predicts postoperative pulmonary infection following D2 radical gastrectomy for gastric cancer.

Introduction: the prognostic nutritional index (PNI) and platelet-lymphocyte ratio (PLR) have been found to correlate with outcomes following radical gastrectomy for gastric cancer (GC). Objectives: to construct a nomogram combining PNI and PLR for individually forecasting the risk of postoperative pulmonary infection (POI) following D2 radical gastrectomy for GC. Methods: retrospectively, clinical data was gathered from 404 patients treated with D2 radical gastrectomy for GC.

[Effects of cypermethrin exposure during lactation of female mice on testicular steroidogenesis in male baby mice].

Objective: To discuss the influence on the testicular steroidogenesis synthesation during baby mice cut-milking period and adult period of male mice by the cypermethrin exposure during lactation of the female mice.

Methods: Fourteen dams of new-born mice were randomly divided into two groups, cypermethrin poisoning group and solution control group. Since the first day after baby delivery, the aternal mice in the cypermethrin poisoning group were given stomach cypermethrin poisoning, using the corn oil as the solution and the poison dose is 25mg! kg, until the 21st day after the delivery when the baby mice has cut-milking.

Maternal cypermethrin exposure during lactation impairs testicular development and spermatogenesis in male mouse offspring.

Within the last decade, numerous epidemiological studies have demonstrated that endocrine disruptors are a possible cause for a decline in semen quality. Cypermethrin is a widely used pyrethroid insecticide, but little is known about its potentially adverse effects on male reproduction. In the present study, we investigated the effects of maternal cypermethrin exposure during lactation on testicular development and spermatogenesis in male offspring.