Publications by authors named "Xinghao Cao"

An outbreak of COVID-19 in Shanghai, China, in March 2022 was caused by the Omicron variant. The epidemic lasted for more than 3 months, and the cumulative number of infected people reached 626,000. We investigated the impact of clinical factors on disease outcomes in patients with COVID-19.

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Background: Most of the biological functions of circular RNAs (circRNAs) and the potential underlying mechanisms in hepatocellular carcinoma (HCC) have not yet been discovered.

Methods: In this study, using circRNA expression data from HCC tumor tissues and adjacent tissues from the Gene Expression Omnibus database, we identified out differentially expressed circRNAs and verified them by qRT-PCT. Functional experiments were performed to evaluate the effects of circFAM13B in HCC in vitro and in vivo.

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Article Synopsis
  • COVID-19 is caused by the SARS-CoV-2 virus and has been labeled a pandemic, affecting many individuals globally.
  • Four cases of COVID-19 were reported where patients tested positive for viral RNA for about 61 days despite receiving various treatments.
  • The antiviral treatment using ritonavir-boosted danoprevir successfully led to two to three consecutive negative test results for SARS-CoV-2 RNA, indicating its potential effectiveness for persistent cases.
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