Observer-based hierarchical distributed model predictive control for multi-linear motor traction systems.

This paper proposes an observer-based hierarchical distributed model predictive control (MPC) strategy for ensuring speed consistency in multi-linear motor traction systems. First, a communication topology is considered to ensure information exchange. Secondly, the control architecture of each agent is divided into upper layers and lower layers.

Prescribed Performance Fault-Tolerant Control for Synchronization of Heterogeneous Nonlinear MASs Using Reinforcement Learning.

In this article, a novel approach of prescribed performance synchronization control is developed for heterogeneous nonlinear multiagent systems (MASs) subject to unknown actuator faults. Considering that not all followers are able to access the information of the leader, a distributed auxiliary perception system is proposed to estimate the state information of the leader to guarantee that the estimation errors converge to zero within fixed time. Then, based on the estimated states, a prescribed performance fault-tolerant control (FTC) approach is proposed, which achieves the user-defined performance specifications even in the presence of system faults.

Inbuilt Tendency of the eIF2 Regulatory System to Counteract Uncertainties.

Eukaryotic initiation factor 2 (eIF2) plays a fundamental role in the regulation of protein synthesis. Investigations have revealed that the regulation of eIF2 is robust against intrinsic uncertainties and is able to efficiently counteract them. The robustness properties of the eIF2 pathway against intrinsic disturbances is also well known.

Distributed fault detection and estimation in cyber-physical systems subject to actuator faults.

The fault detection and estimation problems for the physical layer network in the cyber-physical systems with unknown external disturbances are investigated in this study. Both bias fault and loss of efficiency scenarios are considered for the actuators. Based on the adaptive threshold method and sliding mode observer approach, a distributed fault detection observer (DFDO) is constructed for each physical layer node to detect the occurrence of actuator faults.

Distributed Fault Estimation and Fault-Tolerant Control of Interconnected Systems.

This article studies the distributed fault estimation (DFE) and fault-tolerant control for continuous-time interconnected systems. Using associated information among subsystems to design the DFE observer can improve the accuracy of fault estimation of the interconnected systems. Based on the static output feedback (SOF), the global outputs of the interconnected systems are used to construct a distributed fault-tolerant control (DFTC).

Modeling and Dynamic Behavior of eIF2 Dependent Regulatory System With Disturbances.

Eukaryotic initiation factor 2 (eIF2) is a central controller of the eukaryotic translational machinery. To sustain the on-going translation activity, eIF2 cycles between its GTP and GDP bound states. However, in response to cellular stresses, the phosphorylation of eIF2 takes place, which acts as an inhibitor of the guanine nucleotide exchange factor eIF2B and switches the translation activity on physiological timescales.

Robust Stabilization of T-S Fuzzy Stochastic Descriptor Systems via Integral Sliding Modes.

This paper addresses the robust stabilization problem for T-S fuzzy stochastic descriptor systems using an integral sliding mode control paradigm. A classical integral sliding mode control scheme and a nonparallel distributed compensation (Non-PDC) integral sliding mode control scheme are presented. It is shown that two restrictive assumptions previously adopted developing sliding mode controllers for Takagi-Sugeno (T-S) fuzzy stochastic systems are not required with the proposed framework.

Sliding mode observer based incipient sensor fault detection with application to high-speed railway traction device.

This paper considers incipient sensor fault detection issue for a class of nonlinear systems with "observer unmatched" uncertainties. A particular fault detection sliding mode observer is designed for the augmented system formed by the original system and incipient sensor faults. The designed parameters are obtained using LMI and line filter techniques to guarantee that the generated residuals are robust to uncertainties and that sliding motion is not destroyed by faults.

Computational modelling elucidates the mechanism of ciliary regulation in health and disease.

Background: Ciliary dysfunction leads to a number of human pathologies, including primary ciliary dyskinesia, nephronophthisis, situs inversus pathology or infertility. The mechanism of cilia beating regulation is complex and despite extensive experimental characterization remains poorly understood. We develop a detailed systems model for calcium, membrane potential and cyclic nucleotide-dependent ciliary motility regulation.