The mA methylation and expression profiles of mouse neural stem cells after hypoxia/reoxygenation.

Background: Ischemia-reperfusion injury to the central nervous system often causes severe complications. The activation of endogenous neural stem cells (NSCs) is considered a promising therapeutic strategy for nerve repair. However, the specific biological processes and molecular mechanisms of NSC activation remain unclear, and the role of N6-methyladenosine (mA) methylation modification in this process has not been explored.