The effect of microRNA (miRNA)-19a on gastrointestinal motility in rats with functional dyspepsia was investigated. Fifty adult Sprague-Dawley (SD) rats were randomly divided into 5 groups, 10 rats in each group, one group as the normal group, one group as the model group, and the other three groups were divided into negative control group, miRNA-19a mimic group and miRNA-19a inhibitor group. All rats were intraperitoneally injected with miRNA-19a scramble, miRNA-19a mimic and miRNA-19a inhibitor.
View Article and Find Full Text PDFPurpose: This study aimed to investigate the expression of NOR1 in hepatocellular carcinoma (HCC) tissue and its relationship with prognosis.
Methods: A sample of 60 specimens including HCC and adjacent normal tissues were collected from postoperative HCC patients from February to September 2011. Immunohistochemistry was used to detect the positive expression of the oxidored-nitro domain containing protein 1 (NOR1), the postoperative disease-free survival (DFS) rate and then the overall survival (OS) was analyzed by the Kaplan-Meier method.