Genipin-crosslinked hydrogels for food and biomedical applications: A scientometric review.

Genipin, a precursor of dietary blue pigment, is a promising alternative for industrial applications in food and health. Due to its ability to simultaneously satisfy biosafety requirements and provide crosslinking effects, genipin has attracted considerable attention for food and biomedical applications. In this review, we attempt to shed light on the progress in genipin research using scientometrics.

[Facial soft tissue changes after full-arch implant-supported fixed prostheses restoration in patients with edentulous maxilla].

Purpose: To investigate the changes of nasolabial soft tissues before and after full-arch implant supported fixed restoration in maxillary edentulous patients and the influencing factors of the changes.

Methods: Fifty patients who underwent full-arch implant fixed restoration in the Department of Second Dental Center of Shanghai Ninth People's Hospital from January 2016 to July 2023 were selected. Patient's medical history, CBCT, and three-dimensional facial scan data were collected before and after restoration.

CYP3A4∗18B and CYP3A5∗3 polymorphisms contribute to pharmacokinetic variability of cyclosporine among healthy Chinese subjects.

Aim: Cyclosporine is an immunosuppressant drug used to prevent allograft rejection. It is metabolized by CYP3A4 and CYP3A5, has a narrow therapeutic index, and variable pharmacokinetics. Here, we investigated whether CYP3A5∗3 and CYP3A4∗18B polymorphisms contribute to inter-individual pharmacokinetic variability in healthy subjects.