Publications by authors named "Xing-huan Liang"
Article Synopsis
- Thyroid hormones (THs) have an unclear effect on chronic thyrotoxic myopathy (CTM), prompting a study on their sensitivity and related risks in patients with Graves' disease.
- A total of 162 patients were divided into CTM and non-CTM groups, and various muscle strength and function tests were conducted to assess their relationship with TH sensitivity.
- Results showed that higher sensitivity to THs (measured by TFQI) was linked to an increased risk of CTM, with specific tests like lower-limb fatigue (LLFT) and squat-up (SUT) effectively predicting CTM in male and female patients, respectively.
Primary pigmented nodular adrenocortical disease (PPNAD) is a rare adrenocorticotropin hormone (ACTH)-independent Cushing's syndrome (CS). Pediatric patients with PPNAD typically have unusual skin lesions and slow growth with unknown causes. We present a case of a female Chinese patient with PPNAD caused by the germline PRKACA gene copy number gain of chromosome 19.
View Article and Find Full Text PDFAcute Thyrotoxic Myopathy Combined with Neck Pain: A Case Report.
Neuro Endocrinol Lett
October 2023
Article Synopsis
- Acute thyrotoxic myopathy (ATM) is a rare but serious complication of thyrotoxicosis, typically presenting with bulbar paralysis, and this report highlights the first known Chinese patient with ATM and neck pain.
- The 23-year-old patient experienced progressive weakness and painful thyroid swelling and was diagnosed with ATM, chronic thyrotoxic myopathy, and Graves' ophthalmopathy due to Graves' disease.
- Treatment involved a combination of low-dose glucocorticoids, antithyroid drugs, and an intrathyroidal steroid injection, leading to significant improvement without recurrence of symptoms.
Introduction: Chronic thyrotoxic myopathy (CTM) is a common, easily neglected complication of hyperthyroidism. There are currently no standard diagnostic criteria for CTM, and the ultrasonic characteristics of CTM-affected skeletal muscle remain unclear. Herein, we aimed to evaluate hyperthyroid patients for CTM by ultrasound and identify ultrasonic muscle parameter cutoffs for CTM diagnosis.
View Article and Find Full Text PDFObjective: Intrauterine growth restriction followed by postnatal catch-up growth (CG-IUGR) increases the risk of insulin resistance-related diseases. Low-density lipoprotein receptor-related protein 6 (LRP6) plays a substantial role in glucose metabolism. However, whether LRP6 is involved in the insulin resistance of CG-IUGR is unclear.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess how whole fresh fruit intake affects the risk of developing type 2 diabetes (T2D) in individuals with varying glucose regulation, focusing on a large group of non-diabetic participants aged 40 and older in China.
- Over a follow-up period of 3.8 years, researchers found a significant inverse relationship between fruit consumption and diabetes risk; specifically, each additional 100 grams of fruit consumed daily corresponded to a 2.8% reduction in diabetes risk.
- Results indicated that this protective effect was most pronounced in individuals with normal glucose tolerance, while no significant association was observed in those with prediabetes.
Objective: To survey the status of iodine nutrition and the prevalence of thyroid diseases in Guangxi, China, and to explore the risk factors for positive thyroid antibody.
Methods: We used the multistage stratified cluster random sampling method to select a total of 2488 subjects from an urban and a rural location. All the subjects completed a questionnaire survey, blood and urine samples were also collected, and B-mode thyroid ultrasound was used to determine thyroid function and detect thyroid antibodies.
In children, primary thyroid Burkitt lymphoma (PTBL) is an extremely rare pathologic entity of thyroid malignant tumor. Here we describe a case of PTBL in a 15-year-old boy, who developed a rapidly enlarging neck mass that showed signs of compression. The color Doppler ultrasound revealed diffuse swelling of the thyroid gland, with a solid and irregular mass from the left to the isthmus, which was about 8 × 7 × 5 cm in size.
View Article and Find Full Text PDFBackground: A relationship between hyperthyroidism and insulin secretion in type 2 diabetes mellitus (T2DM) has been reported. Therefore, this study explored the use of first-phase insulin secretion in the differential diagnosis of thyroid diabetes (TDM) and T2DM.
Methods: In total, 101 patients with hyperthyroidism were divided into hyperthyroidism with normal glucose tolerance (TNGT), hyperthyroidism with impaired glucose regulation (TIGR), and diabetes (TDM) groups.
The correlation of plasma omentin-1 with insulin resistance in non-obese polycystic ovary syndrome.
Ann Endocrinol (Paris)
October 2015
Objectives: Aberrant circulating adipokines are considered to be related to the pathological mechanism of polycystic ovary syndrome (PCOS). This study aims to evaluate the relationship between plasma omentin-1 levels, metabolic and hormonal parameters in the setting of non-obese Chinese women with PCOS.
Material And Methods: This was a case-controlled, cross-sectional study of 153 non-obese (BMI<25kg/m(2)) PCOS and 114 age-matched healthy non-obese control individuals.
[Study on association of CTLA4 gene polymorphism with Grave's disease in Guangxi Zhuang nationality population].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
June 2006
Objective: To investigate the relationship between the polymorphic (AT)n repeats in 3ountranslated region of exon 4 of CTLA4 gene [CTLA4(AT)n] and Graveso disease (GD) in Zhuang nationality population of Guangxi province.
Methods: The studied groups comprised 48 patients with GD and 44 normal controls. Amplification of target DNA was carried out by polymerase chain reaction (PCR).