Antibiotic Resistance Genes and Associated Microbial Community Conditions in Aging Landfill Systems.

Landfills receive about 350 million tons of municipal solid wastes (MSWs) per year globally, including antibiotics and other coselecting agents that impact antimicrobial resistance (AMR). However, little is known about AMR in landfills, especially as a function of landfill ages. Here we quantified antibiotics, heavy metals, and AMR genes (ARGs) in refuse and leachates from landfills of different age (<3, 10, and >20 years).

[Analysis of endemic situation of schistosomiasis in Yugan County of Jiangxi Province in 2012].

Objective: To master the epidemic situation and control effect of schistosomiasis in Yugan County, Jiangxi Province.

Methods: The data of the schistosomiasis prevalence in human and cattle as well as Oncomelania hupensis snail status were collected and the change trends were analyzed in Yugan County from 2008 to 2012.

Results: The schistosome infection rates of residents in Yugan County have declined every year since 2008, and currently, the prevalence of schistosomiasis was at a low level.

Sialoendoscopic management of submandibular gland obstruction caused by intraglandular foreign body.

Objective: Submandibular gland obstruction caused by foreign body is relatively uncommon. We discuss the diagnosis and management of foreign body-induced submandibular sialadenitis by an illustrative case report and review of the literature.

Study Design: We report a case of a patient who suffered from obstructive submandibular sialadenitis caused by an intraglandular fish bone, indicating the benefits of sialoendoscopy in diagnosis and treatment of such diseases.

Impact of a nationwide training program for neonatal resuscitation in China.

Background: Seventeen million births occur in China each year. Neonatal mortality is the leading cause of under 5-year-old child deaths, and intrapartum-related injury accounts for much of mental retardation in young children. The Chinese Ministry of Health sought to improve infant and child survival through a nationwide initiative to have at least one person trained in neonatal resuscitation at every birth.

[Clinical characteristics and perinatal outcomes of non-overweight/obese pregnant women with polycystic ovary syndrome].

Objective: To determine clinical characteristics and perinatal outcomes of non-overweight/obese (pre-pregnancy body mass index BMI < 24 kg/m(2)) pregnant women with polycystic ovary syndrome (PCOS).

Methods: The screening of PCOS was performed when they were at first prenatal visit in Beijing Obstetrics and Gynecology Hospital, Capital Medical University from May, 2008 to July, 2010.61 PCOS women of pregnancy women with BMI < 24 kg/m(2) were considered as the study subjects, and 122 pregnant women without PCOS matched by age and pre-pregnancy body mass index (BMI) were selected as the control ones.

Changes of nerve growth factor in amniotic fluid and correlation with ventriculomegaly.

Objective: To detect the change of nerve growth factor (NGF) level in human amniotic fluid during gestation, and to explore the relationship between this change and fetal ventriculomegaly (VM).

Methods: The studied subjects (collected from 2004 to 2007) were divided into four groups, including the second-trimester pregnancy group (n=113), third-trimester pregnancy group (n=110), fetal cerebral VM group (n=12), and healthy control group (n=12) which matched with the VM group in gestational weeks. The amniotic fluid specimens were obtained during amniocentesis or cesarean section.

[Analysis of the perinatal outcomes and management of twin-twin transfusion syndrome].

Objective: To investigate the perinatal outcomes of twin-twin transfusion syndrome (TTTS) and the management.

Methods: During Nov 1, 2002 to Sep 30, 2005, 24 cases of TTTS in Beijing Obstetrics and Gynecology Hospital were analyzed. The outcomes of them were compared with the pregnancy without TTTS in all twins and in monozygotic twins.

The dynamic changes of plasma neuropeptide y and neurotensin and their role in regulating cerebral hemodynamics in neonatal hypoxic-ischemic encephalopathy.

Hypoxic-ischemic encephalopathy (HIE) is a common cause of neonatal encephalopathy and is one of the most important causes of neonatal death and disabilities, especially those infants with moderate to severe encephalopathy. However, the pathogenesis of HIE still remains unclear. The purpose of this study was to explore the dynamic changes in plasma neuropeptide Y (NPY) and neurotensin (NT) as well as their role in regulating cerebral hemodynamics in HIE patients.

The pattern and early diagnostic value of Doppler ultrasound for neonatal hypoxic-ischemic encephalopathy.

This article investigates the value of early diagnosis and prognostic evaluation of Doppler ultrasound for neonatal hypoxic-ischemic encephalopathy (HIE). Study population included 40 term neonates with HIE and 30 healthy controls. Color Doppler ultrasound was performed at the bedside within 24 h after birth.

[Fluid-based thin-layer method for screening of squamous intraepithelial lesions in pregnant women].

Objective: To investigate the clinical significance and safety of liquid-based cytology (thinprep cytologic test, TCT) in pregnant women and cytological characteristics of the smears during pregnancy.

Methods: TCT were performed in 1951 pregnant women (group A), 3752 gynecological out-patients (group B) and 5069 routine screening women (group C). The age of the women was ranged from 20 to 39 years.

Prenatal fetal sex diagnosis by detecting amelogenin gene in maternal plasma.

Objectives: To provide a new, reliable noninvasive method for fetal sex determination.

Methods: Fetal sex was detected in 32 early pregnant women by identifying the amelogenin gene in maternal plasma using nested PCR analysis. First, the 122/128 bp of X-Y homologous region containing 6 bp deletions in the intron 3 of amelogenin gene in X chromosome was amplified, and then the nested PCR was carried out, whose 3' end of the upstream primer is just located in the deletion region.

Association between clinical characteristics and expression abundance of RTKN gene in human bladder carcinoma tissues from Chinese patients.

Purpose: Bladder carcinoma is the most common urological malignancy in China. Gene mutation may be one of causes of carcinogenesis in the cancer. We therefore investigated the mRNA expression of RTKN gene in clinic malignant bladder carcinoma and explored the relationship between the novel gene and the cancer.

Effect of propentofylline on hypoxic-ischaemic brain damage in newborn rat.

Background: Studies showed that propentofylline enhances the action of adenosine and protects hippocampal neuronal damage against transient global cerebral ischaemia. Our study was to investigate the effect of propentofylline on hypoxic-ischaemic brain damage in neonatal rat.

Methods: Seven-day-old Wistar rats were subjected to unilateral common carotid artery ligation and hypoxia in oxygen 8 kPa for two hours at 37 degrees C.

[Study on diagnostic criterion of pregnancy induced hypertension].

Objective: To study the rationality of the current diagnostic criterion of pregnancy induced hypertension (PIH) in mainland China.

Methods: To analytically review the 916 cases of PIH in our hospital, reclassify them using both the current domestic diagnostic criteria and the William Obstetrics' criteria, then compare and analyze perinatal and maternal outcomes from the two standards.

Results: (1) Maternal outcomes: comparison result of the occurrences among three groups of premature birth, postpartum haemorrhage and placental abruption according to domestic classification had significant difference (P < 0.

[Mutation analysis of fibroblast growth factor receptor 3 gene in an achondroplasia family].

Objective: To clarify the patients' pathogenic mechanism in an achondroplasia family not according with the genetic law of autosomal dominant inheritance disease at gene level.

Methods: Genomic DNA from peripheral blood of all members in this family was used for amplification of the exon 10 of fibroblast growth factor receptor 3(FGFR3) gene by PCR; mutation was detected by DNA sequencing and identified by restriction endonuclease MaeIII.

Results: A new mutation of A to T at nucleotide 1180 was found in patients but not in unaffected members.

[Study on intrapartum service model during normal labor].

Objective: To study the availability of humanized service and healthy birth and it's effect on maternal and neonatal outcomes.

Methods: A multicenteral prospective randomized control study was carried out in 9 maternity hospitals from Nov. 2000 to June 2001.

[The blood lead level and pregnant outcome in pregnant women with non-occupational lead exposure].

Objective: The aim of this study is to find out the relations between maternal blood lead and pregnancy complications, neonatal physical and neurobehavioral development respectively.

Methods: 1,151 samples of maternal venous blood and 434 samples of umbilical cord blood were collected. Graphite stove atomic absorption spectrophotometer was used to detect the lead concentration.