Publications by authors named "Xing-Zhong Xia"
Front Pharmacol
February 2019
Article Synopsis
- * Researchers screened around 580,000 compounds and found that anthelmintics like niclosamide and nitazoxanide effectively block TMEM16A, showing better efficacy than traditional β-agonists in harsh conditions, fully bronchodilating airways.
- * This study highlights the potential of repurposing TMEM16A antagonists such as niclosamide and nitazoxanide for treating severe asthma and COPD, as well as possibly expanding their use in cancer and infectious
