Publications by authors named "Xing-Yun Zhao"

Article Synopsis
  • This study investigates how advanced glycation end products (AGEs), harmful compounds linked to chronic diseases, form in glucose-amino acid systems under wet and dry heat conditions.* -
  • Results show that wet heating initially increases concentrations of specific AGEs (CML and CEL) for 90 minutes before they decline, while dry heating leads to a continuous increase in AGE levels over time; cysteine significantly inhibits AGE formation, especially for the Pyr compound.* -
  • While wet heat produces more CML and CEL than dry heat, it creates less Pyr; the research reveals complex interactions between reaction rates and heating methods, emphasizing the potential of cysteine to reduce harmful AGE levels.*
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We present the case of a 58-year-old male patient who presented with pruritic skin plaques and papules on the scalp, face, back, and back of the hands for over a year. The symptoms worsened upon exposure to sunlight and improved on cloudy days. Despite previous attempts at treatment with glucocorticoid ointment and antihistamine drugs, the patient experienced progressive aggravation of symptoms.

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Article Synopsis
  • Hypertrophic scars are problematic after trauma or surgery, affecting both physical appearance and mental health, leading to a need for effective treatments.
  • The study investigates the effects of topical hesperidin, a compound found in citrus fruits with potential benefits against scar formation, using rabbits with induced hypertrophic scars.
  • Results indicated that hesperidin at higher concentrations significantly improved the texture and appearance of scars and reduced the presence of fibroblasts and inflammatory cells compared to other treatments.
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Article Synopsis
  • Acne vulgaris is a widespread skin condition in teens and young adults, often inadequately treated with existing options.
  • Photodynamic therapy (PDT) using 5-Aminolaevulinic acid (ALA) and the biologic drug adalimumab may enhance acne treatment effectiveness due to their complementary effects.
  • A case study demonstrates significant improvement in severe acne after combining ALA-PDT and adalimumab, suggesting potential benefits of this combination for better long-term results.
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We report the case of a 55-year-old man with penile squamous cell carcinoma (SCC). We found a mass in the patient's penis, which gradually increased in size. We performed a partial penectomy to remove the mass.

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Astragali Radix polysaccharides (APSs) have a wide range of biological activities. Our preliminary experiment showed that APS-Ⅱ (10 kDa) was the main immunologically active component of APSs. However, the characteristic structure related to activity of APS-Ⅱ needs further verification and clarification.

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Ion transport through nanochannels is of fundamental importance in voltage-gated protein ion channels and energy storage devices. Direct microscopic observations are critical for understanding the intricacy of ionic processes in nanoconfinement. Here we report an in situ nuclear magnetic resonance study of ion hydration in voltage-gated carbon nanopores.

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Ion distribution in aqueous electrolytes near the interface plays a critical role in electrochemical, biological and colloidal systems, and is expected to be particularly significant inside nanoconfined regions. Electroneutrality of the total charge inside nanoconfined regions is commonly assumed a priori in solving ion distribution of aqueous electrolytes nanoconfined by uncharged hydrophobic surfaces with no direct experimental validation. Here, we use a quantitative nuclear magnetic resonance approach to investigate the properties of aqueous electrolytes nanoconfined in graphitic-like nanoporous carbon.

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A measurement was made on the vertical direction tree ring stable carbon isotope ratio (delta13C) and tree ring width of Pinus sylvestris var. mongolica in northern Daxing' an Mountains of Northeast China, with the relationship between the vertical direction variations of the tree ring delta13C and tree ring width analyzed. In the whole ring of xylem, earlywood (EW) and bark endodermis, the delta13C all exhibited an increasing trend from the top to the base at first, with the maximum at the bottom of tree crown, and then, decreased rapidly to the minimum downward.

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