Importance: Multiple studies indicate a possible correlation between ADD3 rs2501577 and biliary atresia susceptibility; however, a conclusive determination has yet to be made.
Objective: Investigate the role of ADD3 rs2501577 in biliary atresia susceptibility across diverse populations.
Data Sources: The study protocol has been registered on PROSPERO, an international platform for systematic review registration (PROSPERO ID: CRD42023384641).