Publications by authors named "Xing-Qun Cheng"
[Latest Findings on Polyketides/Non-ribosomal Peptides That Are Secondary Metabolites of ].
Sichuan Da Xue Xue Bao Yi Xue Ban
May 2023
Article Synopsis
- Dental caries is a chronic disease affecting tooth structure, primarily caused by bacteria, with a focus on a major pathogen known for its role in caries development.
- Secondary metabolites like bacteriocins and polyketides/non-ribosomal peptides are synthesized by this pathogen, with notable examples being mutanobactin, mutanocyclin, and mutanofactin.
- The review discusses the synthesis, functions, and regulation of these compounds, highlighting their significance in bacterial competition and biofilm formation, and suggesting ways to improve dental caries management.
Saliva is secreted from the salivary glands and has multiple functions, including mouth cleaning and protection, antibacterial effects and digestion. With the rapid advancement in salivaomics, saliva is well recognized as a pool of biological markers. Saliva, as a non-invasive and safe source, could be a substitute for blood in the diagnosis and prognosis of diseases.
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