Publications by authors named "Xing-Peng Di"

Background: Benign prostate hyperplasia (BPH) occurs in elder men globally with high prevalence. Human diet and lifestyle aroused great attention in the prevalence of BPH. Prostate enlargement (PE) is a major symptom of BPH.

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Article Synopsis
  • - The study investigates the mechanisms behind Hunner-type interstitial cystitis (HIC), focusing on urothelial damage and barrier dysfunction, and emphasizes the need for better understanding specific cell types and molecular targets to improve treatment effectiveness.
  • - Using single-cell RNA sequencing, researchers identified eight types of urothelial cells in HIC bladders and found significant loss of UPK3A umbrella cells and increased progenitor-like cells, which struggle to differentiate properly.
  • - The research highlights the TLR3-NR2F6 signaling pathways as key targets for therapeutic interventions, aiming to repair the urothelial barrier and improve bladder function in HIC patients, supported by both lab experiments and real-life testing.
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Background: Kidney stone disease (KSD) is a common condition that affects 10% population in the United States (US). The relationship between thiamine and riboflavin intake and KSD has not been well-studied. We aimed to investigate the prevalence of KSD and the association between dietary thiamine and riboflavin intake with KSD in the US population.

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Fibrosis is a chronic inflammation process with excess extracellular matrix (ECM) deposition that cannot be reversed. Patients suffer from bladder dysfunction caused by bladder fibrosis. Moreover, the interactive mechanisms between ECM and bladder fibrosis are still obscure.

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Background: Paragangliomas (PGLs) are uncommon tumors of uncertain malignant potential. Multifocal paragangliomas are scarcely reported in the literature.

Case Summary: A 25-year-old male patient was reported for the first time with multifocal para-aortic and para-vesical PGLs.

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Introduction And Hypothesis: To identify and compare the top-cited articles from all indexed journals and urology-nephrology and obstetrics-gynecology journals in the Institute for Scientific Information Web of Science's Citation Index Expanded on interstitial cystitis and bladder pain syndrome (IC/BPS).

Methods: Cross-sectional bibliometric analysis of top-cited articles in Web of Science (WoS) from 1900-2022. The articles were retrieved by the MeSH terms from NCBI.

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Introduction And Hypothesis: The objective was to compare the clinical efficacy and safety of pharmacological interventions for interstitial cystitis and bladder pain syndrome (IC/BPS) with direct and indirect evidence from randomized trials.

Methods: We searched PubMed, the Cochrane library, and EMBASE for randomized controlled trials (RCTs) that assessed the pharmacological therapies for IC/BPS. Primary efficacy outcomes included ICSI (O'Leary Sant Interstitial Cystitis Symptom Index), ICPI (O'Leary Sant Interstitial Cystitis Problem Index), 24-h micturition frequency, visual analog scale (VAS), and Likert score for pain.

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Introduction And Hypothesis: The aim of this study was to compare the frequency of metabolic syndrome (MetS) in patients with and without interstitial cystitis/bladder pain syndrome (IC/BPS).

Methods: This case-control study evaluated the indicators of MetS in 287 females with IC/BPS and in 287 females without IC/BPS in West China Hospital between January 2010 and January 2020. Then, the number of voids per day, frequency of night urination, O'Leary-Sant Interstitial Cystitis Symptom/Problem Index, and visual analog scale were examined in the two groups.

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Aims: The aims of this study were to compare surgical results and suture-related complications after uterosacral ligament suspension (USLS) with absorbable suture (AS) vs permanent suture (PS).

Methods: We systematically searched PubMed, Embase, clinicalTrial.gov, and Cochrane Library Central Register of Controlled Trials for articles that compared AS with PS for USLS.

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