Publications by authors named "Xing-Min Han"

Article Synopsis
  • The study looked at how well a special scan (F-PSMA-1007 PET/CT) can predict how serious prostate cancer is based on a grading system called Gleason.
  • Researchers tested 53 patients and found that certain measurements from the scans were really good at telling apart high-grade cancer (more serious) from low-grade cancer (less serious).
  • The key findings were that two specific scan measurements (iPSMA-TV and iTL-PSMA) were the best at predicting the cancer grade and could help doctors understand how to treat it better.
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  • The study investigates the connection between sleep benefit (SB) and dopamine transporter (DAT) levels in the striatum among Parkinson's disease (PD) patients, distinguishing between those with SB and those without (nSB).
  • It analyzed data from 125 PD patients, noting notable differences in various clinical measures, such as sleep efficiency and dopamine uptake, between the SB and nSB groups.
  • The findings reveal significant associations between SB and factors like tremor subtype, medication dosage, and DAT levels, suggesting that higher DAT expression might be linked to the experience of sleep benefits in PD patients.
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To investigate the characteristics and factors that impact the prognosis of Ewing sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) patients. We retrospectively analyzed ES/pPNET patients diagnosed at our hospital from January 2011 to December 2020. We used 1-way analysis of variance to investigate whether the age differences between different subgroups were statistically significant and used the Kaplan-Meier method and Cox regression model for the survival analysis.

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Dysregulation of protein posttranslational modification (PTM) can lead to a variety of pathological processes, such as abnormal sperm development, malignant tumorigenesis, depression, and aging process. SIRT7 is a NAD-dependent protein deacetylase. Besides known deacetylation, SIRT7 may also have the capacity to remove other acylation.

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Objective: The aim of the study was to explore the nature of a V-shaped sign in the backbone of the fifth lumbar vertebra revealed by whole-body bone scintigraphy (WBBS).

Methods: A local single-photon emission computed tomography (SPECT) scan plus a computed tomography (CT) scan were performed on 41 patients in our department who had a V-shaped sign in the backbone of the fifth lumbar vertebra detected by WBBS. Image fusion was conducted to understand the manifestations of the changes in the V-shaped sign in the CT images in WBBS and to determine the nature of the lesion.

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Objective: To establish equations for the estimation of glomerular filtration rates (eGFRs) based on serum creatinine (SCr) and/or serum cystatin C (SCysC) in Chinese patients with chronic kidney disease (CKD), and to compare the new equations with both the reference GFR (rGFR) and the literature equations to evaluate their applicability.

Methods: The 788 Chinese CKD patients were randomly divided into two groups, the training group and the testing group, to establish new eGFR-formulas based on serum CysC and to validate the established formulas, respectively. (99m)Tc-DTPA clearance (as the rGFR), serum Cr, and serum CysC were determined for all patients, and GFR was calculated using the Cockcroft-Gault equation (eGFR1), the MDRD formula (eGFR2), the CKD-EPI formulas (eGFR3, eGFR4), and the Chinese eGFR Investigation Collaboration formulas (eGFR5, eGFR6).

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