Publications by authors named "Xing-Jian Kang"
Arthritis Res Ther
May 2022
Article Synopsis
- Mechanical stress is important for understanding how intervertebral discs (the discs in your spine) can degenerate, and the Piezo1 ion channel helps detect this stress and turn it into chemical signals.
- In experiments, researchers found that high mechanical stress causes problems in cells, like making them less healthy and increasing inflammation, which can harm the discs.
- The study concluded that too much stress increases Piezo1 levels, leading to cell damage and loss of important support structures in the discs, but blocking Piezo1 can help reduce some of the damage.
