[Study on effect of oligochitosan in promoting intestinal absorption of protoberberine alkaloids in extracts from Corydalis saxicola total alkaloids].

Objective: To investigate the effect of oligochitosan in promoting intestinal absorption of protoberberine alkaloids in extracts from Corydalis saxicola total alkaloids.

Method: The in vitro single-pass intestinal perfusion model in rats was established to study the changes in absorption kinetic parameters of dehydrocavidine, berberine hydrochloride and palmatine chloride in C. saxicola total alkaloids after the addition of different concentrations oligochitosan and evaluate the effect of oligochitosan in promoting intestinal absorption of the drugs.

[Irritant stability of raphides and tubers from Pinellia ternate].

Objective: To investigate the irritation stability of raphides from Pinellia ternata and the contribution of raphides proteins on irritation.

Methods: The irritation of raphides and tubers from P. ternata treated with different solvents or protease digestion were evaluated by the Draize test.