Publications by authors named "Xing-Cheng Lin"

Article Synopsis
  • * It works by affecting key signaling pathways, specifically by reducing phosphorylation levels in FAK/AKT and ERK1/2/CREB.
  • * Harmine also promotes cell death (apoptosis) in these cancer cells by regulating proteins like Bcl-2 and Bax, indicating its potential as a treatment for colon cancer.
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Article Synopsis
  • Researchers found that having a messed-up immune system is linked to anxiety disorders.
  • Harmine, a natural compound from some plants, might help reduce anxiety by fighting inflammation in the brain.
  • In experiments with mice, harmine was shown to lower anxiety symptoms and fix the brain's nerve activity that got messed up by inflammation.
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The rhizosphere microbe FD6 possesses beneficial traits such as the production of antibiotics like pyoluteorin (Plt) and 2,4-diacetylphloroglucinol (2,4-DAPG). The alternative RpoS (σ factor), as a master regulator, activates or inhibits the transcription of stationary phase genes in several biocontrol organisms. Here, we investigated the complicated function and regulatory mechanism of RpoS in the biosynthesis of 2,4-DAPG and Plt in strain FD6.

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