Publications by authors named "Xing-Ai Guan"
Background: Babesia duncani is a pathogen within the phylum Apicomplexa that causes human babesiosis. It poses a significant threat to public health, as it can be transmitted not only through tick bites but also via blood transfusion. Consequently, an understanding of the gene functions of this pathogen is necessary for the development of drugs and vaccines.
View Article and Find Full Text PDFWhole-Genome Sequencing, Assembling, Annotation, and Comparative Analysis.
Microbiol Spectr
August 2023
Article Synopsis
- The study sequenced and analyzed the whole genome of the Babesia gibsoni parasite, which causes babesiosis in dogs, revealing a total genome size of 7.94 Mbp and confirming its four chromosomes, apicoplast, and mitochondrion.* -
- Bioinformatics analysis identified thousands of proteins and metabolic pathways, indicating a minimal genome size and revealing specific proteins that may play roles in the parasite's invasion and survival.* -
- This research is significant as it fills gaps in the understanding of B. gibsoni's genetics and evolutionary history, potentially aiding in the development of better diagnostic tools, treatments, and vaccines.*