Protein lactylation in broiler breast: Insights on occurrence mechanisms and the correlations with meat quality.

This study investigated the effects of lactate levels in broiler breast on protein lactylation modification, meat quality, and their correlation. High lactate injections led to increased lactate levels in both serum and breast muscle, and significantly reduced the values of pH, pH and pH. Additionally, the lactylation levels in breast muscle were increased both post-slaughter and post-mortem.

Identification and taste presentation characteristics of umami peptides from soybean paste based on peptidomics and virtual screening.

This research concentrated on soybean paste fermented with Tetragenococcus halophilus, employing peptidomics and machine learning methodologies to screen for novel umami peptides. Taste characteristics of umami peptides were evaluated through sensory evaluation and electronic tongue analysis. The mechanism of taste presentation of the umami peptides was investigated through T1R1/T1R3 molecular docking techniques.

Gastrointestinal protozoa in pet cats from Anhui province: prevalence and molecular characterization.

Introduction: To investigate the prevalence of , , , , , and in domestic cats in Anhui Province, China, and their potential role as zoonotic hosts for human infection, a total of 304 fecal samples from two different sources were screened for the presence of related pathogens.

Methods: Using microscopy, along with polymerase chain reaction (PCR) or nested PCR amplification, followed by genotyping through sequence analysis.

Results: The infection rates of , , , , , and were 5.

HSPG2 could promote normal haematopoiesis in acute myeloid leukaemia patients after complete remission by repairing bone marrow endothelial progenitor cells.

Background: Even after achieving complete remission (CR), many acute myeloid leukaemia (AML) patients suffer from poor haematopoietic recovery after chemotherapy. Previous studies have shown that the damage of bone marrow endothelial progenitor cell (BM EPC) hinders haematopoietic recovery after chemotherapy in mice. Therefore, elucidation of the mechanism and repair strategy of chemotherapy-induced BM EPC damage is urgent needed.

LRP1 mitigates intervertebral disc degeneration by inhibiting endoplasmic reticulum stress through stabilizing the PPARγ.

Background: Intervertebral disc degeneration (IDD) is a significant cause of lower back pain, characterized by inflammation-mediated extracellular matrix (ECM) degradation, apoptosis, and aging of nucleus pulposus (NP) cells. Identifying key regulatory targets for these processes is crucial for IDD treatment. Previous research has highlighted the role of low-density lipoprotein receptor-related protein 1 (LRP1) in regulating ECM levels and cell fate, but its role in IDD remains under-explored.

Temperature-dependent pathways in carbon dioxide electroreduction.

Temperature affects both the thermodynamics of intermediate adsorption and the kinetics of elementary reactions. Despite its extensive study in thermocatalysis, temperature effect is typically overlooked in electrocatalysis. This study investigates how electrolyte temperature influences CO electroreduction over Cu catalysts.

Bone Marrow Endothelial Progenitor Cells remodelling facilitates normal hematopoiesis during Acute Myeloid Leukemia Complete Remission.

Although acute myeloid leukemia (AML) affects hematopoietic stem cell (HSC)-supportive microenvironment, it is largely unknown whether leukemia-modified bone marrow (BM) microenvironment can be remodeled to support normal hematopoiesis after complete remission (CR). As a key element of BM microenvironment, endothelial progenitor cells (EPCs) provide a feasible way to investigate BM microenvironment remodeling. Here, we find reduced and dysfunctional BM EPCs in AML patients, characterized by impaired angiogenesis and high ROS levels, could be partially remodeled after CR and improved by N-acetyl-L-cysteine (NAC).

Spatial transcriptome profiling identifies DTX3L and BST2 as key biomarkers in esophageal squamous cell carcinoma tumorigenesis.

Background: Understanding the stepwise progression of esophageal squamous cell carcinoma (ESCC) is crucial for developing customized strategies for early detection and optimal clinical management. Herein, we aimed to unravel the transcriptional and immunologic alterations occurring during malignant transformation and identify clinically significant biomarkers of ESCC.

Methods: Digital spatial profiling (DSP) was performed on 11 patients with early-stage ESCC (pT1) to explore the transcriptional alterations in epithelial, immune cell, and non-immune cell stromal compartments across regions of distinct histology, including normal tissues, low- and high-grade dysplasia, and cancerous tissues.

Integrated analysis of miRNA and mRNA expression profiles associated with wooden breast myopathy in broiler chickens.

Wooden breast (WB) myopathy has raised a worldwide concern among broiler industry during the past decade. Despite progress in understanding its etiology from transcriptional regulation, post-transcriptional mechanisms including the regulation of microRNAs (miRNAs) remain largely unknown. In the current study, we described an integrative analysis between mRNA and miRNA expression profiles of pectoralis major muscle from normal and WB myopathic broilers.

Insight into the Mechanical Properties and Microstructure of Recycled Aggregate Concrete Containing Carbon Fibers and Nano-SiO.

This study aimed to improve the mechanical properties and microstructure of recycled aggregate concrete (RAC) by incorporating carbon fibers (CFs) and nano-SiO (NS) to promote the optimal utilization of RAC. The mechanical properties of the RAC were enhanced by both single and hybrid additions of CFs and NS, and the hybrid addition had a better strengthening effect. From the experimental results, it was found that the addition of CFs could increase the 28 d compressive strength and splitting strength of the RAC by 9.

Efficient Separation of Oil/Water by a Biodegradable and Superhydrophobic Composite Based on Loofah and Rice Straw.

Membrane filtration is one of the preferred choices for petroleum wastewater disposal due to its simplicity and low energy consumption. In this paper, a biodegradable superhydrophobic membrane based on loofah and rice straw (LF-RS) was prepared and modified with dodecyltriethoxysilane to improve its stability, morphology, and performance. The membrane showed an efficiency of 99.

Dispersion response broadband tunable underwater FMCW blue chirped laser source.

Frequency-modulated continuous-wave (FMCW) narrow linewidth lasers have served as the cornerstone behind applications such as autonomous driving, wearable technology, virtual reality, and remote sensing mapping. Strongly coherent lasers are typically used for these studies, with a clear demand for linear fast response and wide frequency tuning range. In this paper, profiting from the ultrahigh-quality factor of the crystalline whispering-gallery-mode resonator, by using a self-injection locking mechanism to suppress spontaneous emission noise and improve coherence, sub-kHz linewidth at 450 nm is obtained.

Effects of substituting soybean meal with fermented rapeseed meal mixture on the growth performance, slaughter performance, meat quality, blood biochemical indices and intestinal barrier function in Langshan Chickens.

This study aimed to explore the effects of substituting soybean meal with a mixture of solid-state fermented rapeseed meal, apple pomace, and wheat bran on the growth performance, slaughter performance, meat quality, blood biochemical indices and intestinal barrier function of Langshan chickens. A total of 144 30-day-old Langshan chickens with similar body weights were randomly divided into three treatment groups, with six replicates per group and eight chickens per replicate: the control group (CON) was fed a corn-soybean meal basal diet, while the rapeseed meal mixture group (RSM) and the fermented rapeseed meal mixture group (FRSM) were fed diets substituting 5 % of soybean meal with rapeseed meal mixture and fermented rapeseed meal mixture, respectively. The trial lasted from 30 to 58 days of age.

Coated oregano essential oil and cinnamaldehyde compounds supplementation improves growth performance, enhances immune responses, and inhibits cecal Escherichia coli proliferation of broilers.

Plant essential oils are unstable due to high volatility and easy oxidation, while microencapsulation provides a potentially effective strategy for increasing the stability of natural essential oils and preserving their function. This study examined the effects of feeding coated oregano essential oil and cinnamaldehyde (COEC) compounds on growth, immune organ development, intestinal morphology, mucosal immune function, and the cecal microbiota populations of broilers. Three hundred one-day-old male Arbor Acres broiler chicks were organized into 5 groups: 1) negative control fed basal diet alone (NC), 2) positive control receiving basal diet plus 50 mg/kg of chlortetracycline (CTC), 3) basal diet plus 150 mg/kg COEC (COEC150), 4) plus 300 mg/kg COEC (COEC300), and 5) plus 450 mg/kg COEC (COEC450).

Bifunctional system constructed by NiCu-F/DSA electrode self-coupling for efficient removal of ammonia nitrogen from landfill leachate.

Landfill leachates containing high concentrations of ammonia nitrogen, due to its strong toxicity, large discharge and great environmental hazard, is in urgent need of efficient cleaning treatment. In this work, NiCu-F/DSA catalytic electrode was prepared via electrodeposition by means of fluorination-induced surface reconstruction. The surface of electrode was determined to be a porous sponge-like structure by physical characterizations.

Unraveling the role of long non-coding RNAs in chronic heat stress-induced muscle injury in broilers.

Background: Chronic heat stress (CHS) is a detrimental environmental stressor with a negative impact on the meat quality of broilers. However, the underlying mechanisms are not fully understood. This study investigates the effects of CHS on long non-coding RNA (lncRNA) expression and muscle injury in broilers, with a focus on its implications for meat quality.

Bio-based hydrogels induced by salts.

In this study, we introduce a salt-responsive hydrogel system utilizing a sugar-derived surfactant featuring a polyhydroxy spacer in its headgroup. The inclusion of salts enhances and organizes the intermolecular hydrogen bonding within the hydrophilic region of the polyhydroxy spacer, promoting cross-linking among surfactant molecules.

A Comparative Study on the Characteristics of Different Types of Camellia Oils Based on Triacylglycerol Species, Bioactive Components, Volatile Compounds, and Antioxidant Activity.

This study aimed to investigate the characteristics of different varieties of camellia oils and their diacylglycerol (DAG)-enriched derivatives in terms of triacylglycerol (TAG) species, bioactive components, volatile compounds, and antioxidant activity. Six types of camellia oils, including (C.O), (C.

Switching CO Electroreduction Pathways between Ethylene and Ethanol via Tuning Microenvironment of the Coating on Copper Nanofibers.

Engineering the microenvironment of electrode surface is one of the effective means to tune the reaction pathways in CORR. In this work, we prepared copper nanofibers with conductive polypyrrole coating by polymerization of pyrrole using polyvinyl pyrrolidone (PVP) as template. As a result, the obtained copper nanofibers Cu/CuO/SHNC, exhibited a superhydrophobic surface, which demonstrated very high selectivity for ethanol with a Faraday efficiency (FE) of 66.

Three-dimensional atomic insights into the metal-oxide interface in Zr-ZrO nanoparticles.

Metal-oxide interfaces with poor coherency have specific properties comparing to bulk materials and offer broad applications in heterogeneous catalysis, battery, and electronics. However, current understanding of the three-dimensional (3D) atomic metal-oxide interfaces remains limited because of their inherent structural complexity and the limitations of conventional two-dimensional imaging techniques. Here, we determine the 3D atomic structure of metal-oxide interfaces in zirconium-zirconia nanoparticles using atomic-resolution electron tomography.