Publications by authors named "Xing Feng"

Background: Post-stroke rehabilitation exercise is recognized as the most effective and preferred intervention to reduce disability rates in patients. However, adherence to exercise is low among stroke patients. Previous research has mainly focused on the negative psychological factors influencing adherence, while the positive psychological aspects remain underexplored.

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Leaf trichome formation is a very important agronomic trait as it confers resistance to biotic and abiotic stresses, but the causal genes involved in this process in remain largely unexplored. In this study, we first characterized the haplotypes of among different inbred lines with leaf trichomes or glabrous leaves. A comparative analysis of the number and density of leaf trichomes between the two mustard inbred lines was then performed BSA analysis of leaves with trichomes and glabrous pools from the F2 segregating population mapped the candidate genes on Chr.

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Light-harvesting antenna systems (AS) with multiple light-absorbing chromophores play a vital role in absorbing sunlight and transferring the excitation energy to the reaction centers during the photosynthesis process. Learning from nature, a set of simple and artificial pyrene-based light-harvesting antenna systems have been designed and re-examined from the self-developing chemical intermediates, via combining the electron-donating 4,4-dimethoxy-triphenylamine moieties as the antenna for absorbing energy donors and transferring to the reaction center. These pyrene-based light-harvesting antenna systems exhibit a positive correlation between the molar absorption coefficient (ε), enhanced photoluminescence efficiency with unchanged emission peak, and two-photon absorption cross-section with an increasing number of antenna of TPA-OMe moieties in solution.

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Kawasaki Disease (KD) is an acute and self-limiting vasculitis of unknown etiology that mainly occurs in infancy and can lead to vascular endothelial injury. Hesperidin (HES) is an economical dietary biological flavonoid with anti-oxidant, anti-inflammatory, and anti-apoptotic pharmacological effects. The main objective of this study was to investigate the protective effects of HES on KD, and try to elucidate the underlying mechanism.

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In coastal areas, the presence of concrete cracks provides pathways for hazardous ions to ingress from the exterior into the interior of concrete, while the migration of the ions further accelerates concrete deterioration and causes durability problems. The incorporation of graphene oxide (GO) into concrete can inhibit crack initiation and development starting at the nanoscale, improving the concrete microstructure, thereby affecting concrete's resistance to hazardous ion transport and the resulting deterioration. In this study, a multi-scale transport model for cementitious materials with a GO admixture was established to predict the resistance to hazardous ions.

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Background: Rebleeding after recovery from esophagogastric variceal bleeding (EGVB) is a severe complication that is associated with high rates of both incidence and mortality. Despite its clinical importance, recognized prognostic models that can effectively predict esophagogastric variceal rebleeding in patients with liver cirrhosis are lacking.

Aim: To construct and externally validate a reliable prognostic model for predicting the occurrence of esophagogastric variceal rebleeding.

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Embryonic hematopoietic cells develop in the fetal liver (FL), surrounded by diverse non-hematopoietic stromal cells. However, the spatial organization and cytokine production patterns of the stroma during FL development remain poorly understood. Here, we characterized and mapped the hematopoietic and stromal cell populations at early (E12.

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(1) Background: The Hu sheep is a renowned breed characterized by high reproduction, year-round estrus, and resistance to high humidity and temperature conditions. However, the breed exhibits lower growth rates and meat yields, which necessitate improvements through selective breeding. The integration of molecular markers in sheep breeding programs has the potential to enhance growth performance, reduce breeding cycles, and increase meat production.

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Aims: Hypertrophic cardiomyopathy (HCM) is characterized by unexplained left ventricular hypertrophy (LVH) with key pathologic processes including myocardial necrosis, fibrosis, inflammation, and hypertrophy, which are involved in heart failure (HF), stroke, and even sudden death. Our aim was to explore the communication network among various cells in the heart of transverse aortic constriction (TAC) surgery induced HCM mice.

Materials And Methods: Single-cell RNA-seq data of GSE137167 was downloaded from the Gene Expression Omnibus (GEO) database.

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Porous eco-concrete (PEC) can achieve safety protection and ecological protection. This study utilized cold-bonded lightweight aggregates (CBLAs) as coarse aggregates and improved the PEC preparation process via the disc shell-making method. The compressive strength, void ratio, pH value, sand permeability, and plant growth of PECs were studied.

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Article Synopsis
  • - Neuroinflammation caused by microglia is a major factor in neurodegenerative diseases, and Lappaconitine (LA), derived from a plant, has been found to reduce certain inflammatory responses in cells.
  • - Researchers synthesized and tested LA analogues for their ability to inhibit nitric oxide production in microglia, with one compound (compound 10) showing the strongest effect.
  • - Compound 10 works by inhibiting a specific inflammatory pathway in microglia and appears to be safer than LA in toxicity tests, suggesting it could be a promising candidate for treating neuroinflammation.
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Background: Periostin mediates inflammation and fibrosis by regulating extracellular matrix adhesion, migration, and differentiation in multiple organ diseases. Studies have shown periostin mainly located in the dilated mesangium, tubulointerstitial and fibrotic regions of the diabetic kidney disease, which was negatively correlated with renal function. However, the underlying mechanism remains poorly explored.

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Background: Sugars Will Eventually be Exported Transporter (SWEET) gene family is a unique type of sugar transporter that plays a vital role in metabolic regulation, growth, development, and stress response in multiple species. This study aimed to systematically identify the SWEET gene family members and detect the regulation of gene expression and their potential roles of the SWEET gene family in Brassica juncea.

Results: A total of 66 BjSWEET (Brassica juncea Sugar Will Eventually be Exported Transporter) genes distributed across 17 chromosomes were identified.

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Article Synopsis
  • The study focuses on understanding the genetic factors that influence lamb production, specifically comparing single lamb (SLE) and twin lamb (TLE) traits in Hotan sheep.
  • Researchers utilized genome-wide resequencing to analyze the genomes, assessing genetic differentiation and nucleotide diversity related to lambing traits, and identified 290 selected regions linked to these traits.
  • The findings reveal 13 key genes related to lambing rates, with significant pathways implicated, which may serve as molecular markers to improve sheep reproduction and support conservation efforts.
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Light-field particle imaging velocimetry (LF-PIV) is widely used in large-scale flow field measurement scenarios due to its instant 3D imaging capability. However, conventional LF-PIV systems suffer low axial resolution and thereby have limited application in high-resolution and volumetric velocity measurements. Here, we report the use of synthetic color-and-depth-encoded (sCade) illumination to improve the axial resolution of LF-PIV.

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Generic substitutions are globally considered to contain health expenditures. Yet it is uncertain whether the costs spill over to other medicines or health services. Contextualizing China's National Volume-Based Procurement (NVBP) policy, which promoted generic substitution, this study tests the changes in patients' utilization of generic medicines and whether the costs shift to other pharmaceutics or health services post-policy.

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Article Synopsis
  • Research involved various assays (like PCR and Western blot) to analyze the relationship between Lnc NEAT1, miR-152-3p, and CDK6, revealing that Lnc NEAT1 is positively linked to CDK6 and negatively linked to miR-152-3p.
  • The study concluded that Lnc NEAT1 promotes melanoma cell growth and migration by acting as a sponge for miR-152-3p, leading to increased CDK6 levels, highlighting its potential as a target for melanoma treatment.
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Objectives: To assess trends and differences in child malnutrition by population subgroups among infants aged 6-23 months in China's poorest rural counties.

Design: Six consecutive cross sectional surveys were conducted annually.

Setting: The study was conducted in 116 counties in 19 provinces from 2016 to 2021, representing China's 832 poorest counties.

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Objective: This study aimed to preliminary explore the molecular mechanisms of Houttuynia cordata Thunb. (H. cordata; Saururaceae) in treating non-small cell lung cancer (NSCLC), with the goal of screening drug potential targets for clinical drug development.

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Mutations in genes coding sarcomere components are the major causes of human inherited cardiomyopathy. Genome editing is widely applied to genetic modification of human pluripotent stem cells (hPSCs) before hPSCs were differentiated into cardiomyocytes to model cardiomyopathy. Whether genetic mutations influence the early hPSC differentiation process or solely the terminally differentiated cardiomyocytes during cardiac pathogenesis remains challenging to distinguish.

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Article Synopsis
  • The study investigated the neonatal outcomes of preterm infants (24-31 weeks gestational age) in 57 hospitals across China, focusing on how birth weight for gestational age affects health risks.
  • It included 8,380 infants, finding that lower birth weight was linked to higher risks of serious health issues like mortality, necrotizing enterocolitis, and bronchopulmonary dysplasia.
  • The research concluded that infants with birth weights below the 30th percentile face significantly higher risks for adverse outcomes, highlighting the need for close monitoring and early intervention for these vulnerable infants.
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Alcohol sensing plays a critical role in medical detection and personal health management. AIE materials with high sensitivity, selectivity and fast response have been widely used in biosensing, but their application in the field of alcohol sensing still needs further research and development. Furthermore, developing flexible phase change materials (PCMs) is significant for the research of human-body thermal management.

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Vanadium flow batteries (VFBs) are considered one of the most promising candidates for large-scale energy storage. However, VFBs suffer from relatively low power density due to severe electrochemical polarization. Herein, we report Bi single atoms supported by an N-doped carbon-regulated graphite felt electrode (Bi SAs/NC@GF) with high electrocatalytic activity and stability, owing to the greatly improved active sites and optimized Bi-N configuration.

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Background: Kawasaki disease (KD) is a self-limiting and acute systemic vasculitis of unknown etiology, mainly affecting children. Ferulic acid (FA), a natural phenolic substance, has multiple pharmacological properties, including anti-inflammatory, anti-apoptosis, and anti-fibrosis, and so on. So far, the protective effects of FA on KD have not been explored.

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