Development and validation of a nomogram predicting multidrug-resistant tuberculosis risk in East China.

Objective: Multidrug-resistant tuberculosis (MDR-TB) is a global health threat. Our study aimed to develop and externally validate a nomogram to estimate the probability of MDR-TB in patients with TB.

Methods: A total of 453 patients with TB in Anhui Chest Hospital between January 2019 and December 2020 were included in the training cohort.

Neuroprotective effect and possible mechanisms of the extract of ginkgo biloba for spinal cord injury in experimental animal: a meta-analysis and systematic review.

Spinal cord injury (SCI) is a major challenge in the medical community because of its difficulty in treatment and poor prognosis. Extract of ginkgo biloba (EGb) has been widely used in the prevention and treatment of age-related neurosensory disease, which is considered to have the effect of neuroprotection. We performed a systematic review to evaluate the neurobiological roles of EGb for treating SCI in rats.

A study of the mediating effect of self-perceived burden between meaning in life and dignity in disabled patients based on a dignity theory model.

Objective: To explore the mediating role of self-perceived burden between meaning in life and the level of dignity in patients with disability.

Methods: From July to October 2023, 229 disabled patients in a tertiary hospital in Sichuan Province, China were selected and surveyed using the Self-Perceived Burden Scale, Meaning in Life Questionnaire, and Patient Dignity Inventory.

Results: The levels of self-perceived burden, meaning of life, and dignity of the disabled patients were 23.

High-temperature structural disorders stabilize hydrous aluminosilicates in the mantle transition zone.

Hydrous aluminosilicates are important deep water-carriers in sediments subducting into the deep mantle. To date, it remains enigmatic how hydrous aluminosilicates withstand extremely high temperatures in the mantle transition zone. Here we systematically investigate the crystal structures and chemical compositions of typical hydrous aluminosilicates using single-crystal X-ray diffraction, electron probe microanalyzer, and nanoscale secondary ion mass spectrometry.

Ultrafast humidity sensor and transient humidity detections in high dynamic environments.

Limited by the adsorption and diffusion rate of water molecules, traditional humidity sensors, such as those based on polymer electrolytes, porous ceramics, and metal oxides, typically have long response times, which hinder their application in monitoring transient humidity changes. Here we present an ultrafast humidity sensor with a millisecond-level response. The sensor is prepared by assembling monolayer graphene oxide quantum dots on silica microspheres using a simple electrostatic self-assembly technique.

Career adaptability and correlating factors among secondary vocational nursing students in China.

Background: Career adaptability significantly affects college students' career happiness in the future, and it is essential to make a detailed evaluation of its correlation for making a targeted intervention plan. However, the applicability of occupational adaptability to secondary vocational nursing students is still an unexplored field in academic research.

Objective: This study aimed to investigate the current situation of career adaptability and its influencing factors on secondary vocational nursing students in medical schools.

Development of a core outcome set of clinical research on the integration of traditional Chinese and Western medicine for spinal metastases: .

Background: In recent years, the incidence of spinal metastasis (SM) has been increasing steadily. In response to this serious public health problem, researchers have made progress by using the integration of traditional Chinese and Western medicine. However, considerable heterogeneity in the definition and measurement of outcomes across clinical research studies, along with the lack of uniform measurement standards for study data, makes it difficult for researchers to compare different treatments.

Droplet Micro-Sensor and Detection of Respiratory Droplet Transmission.

Droplet transmission is the primary infection route for respiratory diseases like COVID-19 and influenza, but small and low-cost wearable droplet detection devices are a significant challenge. Herein, a respiratory droplet micro-sensor based on graphene oxide quantum dots (GOQDs) assembled onto SiO microspheres by the nebulized natural deposition is presented. Benefiting from the energy dissipation of the microsphere to droplets, the sensor can detect droplets as far as 2 m from coughing.

A Conceptual Framework to Understand the Self-Assembly of Chemically Active Colloids.

Colloids that generate chemicals, or "chemically active colloids", can interact with their neighbors and generate patterns via forces arising from such chemical gradients. Examples of such assemblies of chemically active colloids are abundant in the literature, but a unified theoretical framework is needed to rationalize the scattered results. Combining experiments, theory, Brownian dynamics, and finite element simulations, we present here a conceptual framework for understanding how immotile, yet chemically active, colloids assemble.

Cross-Cultural Adaptation of the Neck Bournemouth Questionnaire: A Methodological Systematic Review.

Objective: Neck pain is a common musculoskeletal disorder, and it affects the quality of life of patients. As an effective and reliable multidimensional measurement tool for neck pain, the Neck Bournemouth Questionnaire (NBQ) has been cross-culturally adapted into multiple languages for clinical practice. The aim of this study was to evaluate the translation procedures and measurement properties of cross-cultural adaptations of the NBQ.

A critical appraisal of clinical practice guidelines on surgical treatments for spinal metastasis.

Purpose: As an important treatment for spinal metastasis, surgery has strict applicable conditions. Although various organizations have formulated different guidelines on surgical treatment for spinal metastasis (SM), there are certain differences in the content, standardization and quality of the guidelines and it is necessary to make a critical appraisal of them. We aim to systematically review and appraise the current guidelines on surgical treatments of SM and summarize the related recommendations with the quality evaluation of supporting evidence, as to provide a reference for the standardization of surgical treatment plans, and help clinical front-line medical workers can make safe and effective clinical decisions faster.

Correlations of IL-1β and vitamin D with CAT score in patients with acute exacerbation of chronic obstructive pulmonary disease.

This study was to analyze the correlations of IL-1β and vitamin D (VitD) with chronic obstructive pulmonary disease assessment test (CAT) score in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). For this purpose, a total of 65 patients with chronic obstructive pulmonary disease (COPD) treated in our hospital between June 2020 and June 2022 were enrolled and assigned to a research group, and 40 healthy individuals who underwent physical examination in our hospital over the same time spanning were enrolled into the control group. The 65 COPD patients were further grouped into a stability group (30 cases) and an exacerbation group (35 cases).

A systematic review and meta-analysis of chondroitinase ABC promotes functional recovery in rat models of spinal cord injury.

Background: To comprehensively assess the neurologic recovery potential of chondroitinase ABC (ChABC) in rats after spinal cord injury (SCI).

Methods: The PubMed, Embase, ScienceDirect, Web of Science, and China National Knowledge Infrastructure databases were searched for animal experiments that evaluated the use of ChABC in the treatment of SCI up to November 2022. Studies reporting neurological function using the Basso, Beattie, and Bresnahan (BBB) scale, as well as assessments of cavity area, lesion area, and glial fibrillary acidic protein (GFAP) levels, were included in the analysis.

Measurement properties of health-related quality of life measures for people living with metastatic disease of the spine: a systematic review.

Purpose: Patients with spinal metastases (SM) suffer from a significant quality of life (QoL) deterioration. The measurement of QoL has garnered significant attention. In this study, the authors aimed to investigate the frequency of QoL measurement, systematically appraise the measurement properties of identified instruments, and facilitate the effective selection of an appropriate QoL instrument for patients with SM.

Berry Curvature and Bulk-Boundary Correspondence from Transport Measurement for Photonic Chern Bands.

Berry curvature is a fundamental element to characterize topological quantum physics, while a full measurement of Berry curvature in momentum space was not reported for topological states. Here we achieve two-dimensional Berry curvature reconstruction in a photonic quantum anomalous Hall system via Hall transport measurement of a momentum-resolved wave packet. Integrating measured Berry curvature over the two-dimensional Brillouin zone, we obtain Chern numbers corresponding to -1 and 0.

Supplementation of chestnut tannins in diets can improve meat quality and antioxidative capability in Hu lambs.

Chestnut tannins (CNT), as a source of hydrolyzable tannins, positively affect the antioxidant status of livestock. In the current study, 90 male Hu lambs were used to investigate the effect of dietary CNT intake on growth performance, nutrient digestibility, meat quality and oxidative stability, rumen microbial, and the transcriptomes of muscle and liver. A completely randomized design with three CNT intake levels (0, 0.

Bibliometric Insights in Advances of Chordoma: Global Trends and Research Development in the Last Decade.

Chordoma is a rare tumor, but has a serious effect on the quality of life of patients. This study aims to assess the overall knowledge structure and trends in the development of chordoma research using a bibliometric analysis and visualization tool. Research datasets were acquired from the Web of Science.

GIONet: Global information optimized network for multi-center COVID-19 diagnosis via COVID-GAN and domain adversarial strategy.

The outbreak of coronavirus disease (COVID-19) in 2019 has highlighted the need for automatic diagnosis of the disease, which can develop rapidly into a severe condition. Nevertheless, distinguishing between COVID-19 pneumonia and community-acquired pneumonia (CAP) through computed tomography scans can be challenging due to their similar characteristics. The existing methods often perform poorly in the 3-class classification task of healthy, CAP, and COVID-19 pneumonia, and they have poor ability to handle the heterogeneity of multi-centers data.

The critical impacts of pyrochar during 2,4,6-trichlorophenol photochemical remediation process: Cooperation between persistent free radicals and oxygenated functional groups.

The widespread use of polychlorophenols poses enormous environmental challenges. Biochar has the potential to accelerate the transformation of polychlorophenols. But the biochar-triggered photochemical decomposition mechanism of polychlorophenols still remains unclear.

Association between loop electrosurgical excision procedure and adverse pregnancy outcomes: a meta-analysis.

Objective: To assess the association between loop electrosurgical excision procedure (LEEP) and adverse pregnancy outcomes.

Methods: The databases including PubMed, Embase, Cochrane Library and Web of science were searched from inception to December 27th, 2020. Odds ratio (OR) and 95% confidence interval (CI) were utilized to calculate the association between LEEP and adverse pregnancy outcomes.