The Emerging Role of IGF2BP2 in Cancer Therapy Resistance: From Molecular Mechanism to Future Potential.

Tumor resistance is one of the primary reasons for cancer treatment failure, significantly limiting the options and efficacy of cancer therapies. Therefore, overcoming resistance has become a critical factor in improving cancer treatment outcomes. IGF2BP2, as a reader of m6A methylation, plays a pivotal role in the post-transcriptional regulation of RNA through the methylation of m6A sites.

Recent progress in Si/TiCT MXene anode materials for lithium-ion batteries.

Cardiovascular diseases (CVDs) are a major global health issue, causing significant morbidity and mortality worldwide. Early diagnosis and continuous monitoring of physiological signals are crucial for managing cardiovascular diseases, necessitating the development of lightweight and cost-effective wearable devices. These devices should incorporate portable energy storage systems, such as lithium-ion batteries (LIBs).

Exact New Mobility Edges between Critical and Localized States.

The disorder systems host three types of fundamental quantum states, known as the extended, localized, and critical states, of which the critical states remain being much less explored. Here we propose a class of exactly solvable models which host a novel type of exact mobility edges (MEs) separating localized states from robust critical states, and propose experimental realization. Here the robustness refers to the stability against both single-particle perturbation and interactions in the few-body regime.

Nanozyme Inhibited Sensor Array for Biothiol Detection and Disease Discrimination Based on Metal Ion-Doped Carbon Dots.

Developing highly active and sensitive nanozymes for biothiol analysis is of vital significance due to their essential roles in disease diagnosis. Herein, two metal ion-doped carbon dots (M-CDs) with high peroxidase-like activity were designed and prepared for biothiol detection and identification through the colorimetric sensor array technique. The two M-CDs can strongly catalyze the decomposition of HO, accompanied by color changes of 3,3',5,5'-tetramethylbenzidine (TMB) from colorless to blue, indicating peroxidase-mimicking activities of M-CDs.

The Progress of Hard Carbon as an Anode Material in Sodium-Ion Batteries.

When compared to expensive lithium metal, the metal sodium resources on Earth are abundant and evenly distributed. Therefore, low-cost sodium-ion batteries are expected to replace lithium-ion batteries and become the most likely energy storage system for large-scale applications. Among the many anode materials for sodium-ion batteries, hard carbon has obvious advantages and great commercial potential.