Publications by authors named "Xinchao Jiang"
Article Synopsis
- The study analyzed the effectiveness of the self-locking cage (ROI-C) compared to a conventional cage-plate (CCP) for treating spinal cord injuries without fractures or dislocations, reviewing 83 patients.
- Results showed no significant differences in blood loss, improvement measures, or cervical lordosis between the two groups, but significant differences were found in disc height and T1 slope.
- Ultimately, both methods achieved bony fusion, but ROI-C demonstrated stable fixation without cage migration at the final follow-up, highlighting its equivalent efficacy in cervical stability.
Objective: Knee osteoarthritis (KOA) is a chronic condition characterized by persistent pain that can lead to severe disability. In this study, we primarily investigated the analgesic effect of Huojing decoction on MIA-induced knee arthritis.
Methods: The network pharmacology method was employed to acquire target information of Huojing decoction and KOA.
Bone cancer pain could lead to pain sensitization. Traditional Chinese Medicine could relieve bone cancer pain (BCP). This study aimed to investigate the analgesic effect of Bushen Tongluo decoction on rats with BCP and its impact on ERK/c-fos pathway in spinal dorsal horn.
View Article and Find Full Text PDFEndoplasmic reticulum stress (ERS) is a new pathway inducing cell apoptosis that has been discovered in recent years. This study focused on the protective effect of Liangxue Huayu recipe (LHR) on tumor necrosis factor-alpha (TNF-alpha) and D-GalN-induced hepatocyte apoptosis. It found that TNF-alpha and D-GalN could obviously inhibit hepatocyte proliferation, induce cell apoptosis, and significantly increase free calcium ions in cytoplasms, as well as protein expressions of ERS apoptosis-related signal molecules phosphorylated PERK, phosphorylated elF2alpha, cleaved Caspase-12, GRP78 and CHOP.
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