Publications by authors named "Xinbo Deng"
MiRNAs are related to neuronal proliferation and apoptosis following cerebral ischemia-reperfusion injury (CIRI). This study focused on miR-30c-5p in the disease. An oxygen-glucose deprivation/re-oxygenation (OGD/R) model was prepared in HT22 cells and transfected to overexpress miR-30c-5p and G Protein Subunit Alpha I2 (GNAI2) respectively or co-transfected to silence miR-30c-5p and GNAI2.
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- The study found that Chinese patients with multiple sclerosis (MS) had higher blood levels of homocysteine (Hcy) and lower levels of vitamin B12 (VB12) compared to control groups, suggesting a potential correlation between these lab values and MS.
- Results indicated no significant difference in folate levels between MS patients and controls.
- The meta-analysis reinforces these findings, showing increased Hcy and decreased VB12 specifically in relapsing MS patients compared to controls.
To perform a meta-analysis to help resolve the controversy of whether the Angiogenin (ANG) rs11701 polymorphism is associated with amyotrophic lateral sclerosis (ALS) risk. A literature search of PubMed, Embase, Web of Science, Chinese National Knowledge Infrastructure, Wanfang and SinoMed was conducted for eligible studies published up to Jun 5, 2015. The strength of the association between the polymorphism and ALS susceptibility was estimated by odds ratio (OR) and associated 95 % confidence interval (CI).
View Article and Find Full Text PDFThe study purpose is to perform a meta-analysis to help resolve the debate of whether the Angiogenin (ANG) K17I variant is associated with amyotrophic lateral sclerosis (ALS) risk in Caucasian. Three literature databases were searched for eligible studies published up to January 8, 2015: PubMed, Embase and Web of Science using the following search terms: amyotrophic lateral sclerosis or ALS and Angiogenin or ANG. Five eligible articles were identified, which reported 6 case-control studies and a total of 2326 cases and 3799 controls.
View Article and Find Full Text PDF[Six cases of benign recurrent vertigo from a family].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
June 2015
Purpose: To perform a meta-analysis to help resolve the controversy of whether the ATP13A2 A746T variant is associated with Parkinson's disease (PD) susceptibility in Han Chinese.
Methods: Six literature databases were searched for case-control studies published up to October 2014: Web of Science, PubMed, Embase, Chinese National Knowledge Infrastructure, Wanfang and SinoMed.
Results: Five eligible articles were identified, which reported six case-control studies and a total of 1703 cases and 2050 controls.