Characteristics of Vulvo-Vaginal Infections in 9- to 13-Year-Old Girls Undergoing Rapid Puberty.

Background: This study was conducted to investigate the characteristics of vulvo-vaginal infections in 9- to 13-year-old girls undergoing rapid puberty.

Methods: Three hundred ninety girls aged 9 - 13 years who experienced vulvo-vaginal infections while undergoing rapid puberty and were treated at West China Second University Hospital from July 2017 to June 2020 were retrospectively analyzed. The incidences of bacterial vaginosis (BV), intermediate BV, and vulvo-vaginal candidiasis (VVC) and the differences in these incidences for patients of different ages were analyzed.

Inhibition of cervical cancer cells by co-culturing with mesenchymal stem cells.

The effect of mesenchymal stem cells (MSCs) on tumors remains controversial and requires further exploration. In this study, we isolated MSCs from umbilical cord (UC) and co-cultured with cervical cancer HeLa cells. Flow cytometry was conducted to detect apoptosis and cell cycle.

The dynamic changes of vaginal microecosystem in patients with recurrent vulvovaginal candidiasis: a retrospective study of 800 patients.

Purpose: Vaginal microecological environment is an important factor of recurrent vulvovaginal candidiasis (RVVC). This study was undertaken to investigate dynamic changes of vaginal microecosystem in patients with RVVC.

Methods: Four hundred patients with VVC and 400 healthy women of reproductive age who admitted to the hospital from January 2012 to December 2013 were evaluated retrospectively.

Prospective, sequential, longitudinal study of coagulation changes during pregnancy in Chinese women.

Objective: To investigate changes and establish reference values for coagulation variables during normal pregnancy and after delivery in Chinese women.

Methods: A prospective, sequential, longitudinal study with strict inclusion and exclusion criteria was performed with 232 Chinese women.

Results: Prothrombin time, international normalized ratio, activated partial thromboplastin time, and activated partial thromboplastin time ratio were shorter, and platelet count decreased gradually during pregnancy, with no change in mean platelet volume; conversely, plasma concentration of both fibrinogen and fibrin/fibrinogen degradation product increased.